Recombinant Human CCL28 Protein | R&D Systems 717-VC product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human CCL28 Protein

catalog :

717-VC

quantity :

25 ug

price :

239 USD

citations: 7

Reference
Karnezis T, Farnsworth R, Harris N, Williams S, Caesar C, Byrne D, et al. CCL27/CCL28-CCR10 Chemokine Signaling Mediates Migration of Lymphatic Endothelial Cells. Cancer Res. 2019;79:1558-1572 pubmed publisher
Huang G, Tao L, Shen S, Chen L. Hypoxia induced CCL28 promotes angiogenesis in lung adenocarcinoma by targeting CCR3 on endothelial cells. Sci Rep. 2016;6:27152 pubmed publisher
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher
Pacheco Rodriguez G, Kumaki F, Steagall W, Zhang Y, Ikeda Y, Lin J, et al. Chemokine-enhanced chemotaxis of lymphangioleiomyomatosis cells with mutations in the tumor suppressor TSC2 gene. J Immunol. 2009;182:1270-7 pubmed
Nakayama T, Shirane J, Hieshima K, Shibano M, Watanabe M, Jin Z, et al. Novel antiviral activity of chemokines. Virology. 2006;350:484-92 pubmed
Hieshima K, Ohtani H, Shibano M, Izawa D, Nakayama T, Kawasaki Y, et al. CCL28 has dual roles in mucosal immunity as a chemokine with broad-spectrum antimicrobial activity. J Immunol. 2003;170:1452-61 pubmed
Huber T, Reinhardt H, Exner M, Burger J, Kerjaschki D, Saleem M, et al. Expression of functional CCR and CXCR chemokine receptors in podocytes. J Immunol. 2002;168:6244-52 pubmed

product information

brand :

R&D Systems

master code :

717-VC

SKU :

717-VC-025

product name :

Recombinant Human CCL28 Protein

description :

The Recombinant Human CCL28 Protein from R&D Systems is derived from E. coli. The Recombinant Human CCL28 Protein has been validated for the following applications: Bioactivity.

target :

CCL28

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

theoretical molecular weight :

12 kDa

gene symbol :

CCL28

details of functionality :

Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CCR10. The ED50 for this effect is 0.4-2.0 µg/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

catalog number base :

717-VC

accessionNumbers :

Q9NRJ3

applications :

Bioactivity

source :

E. coli -derived human CCL28 protein Ile23-Tyr127

2020 USD :

239

2021 USD :

239 USD

alt names :

CCL28, chemokine (C-C motif) ligand 28, MEC, member 28, MGC71902, Protein CCK1, VIC

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.