Recombinant Human CCL28 Protein | R&D Systems 717-VC-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human CCL28 Protein

catalog :

717-VC-025

quantity :

25 ug

price :

269 USD

more info or order :

R&D Systems product webpage

citations: 8

Reference
Nayrac M, Requena M, Loiseau C, Cazabat M, Suc B, Carrere N, et al. Th22 cells are efficiently recruited in the gut by CCL28 as an alternative to CCL20 but do not compensate for the loss of Th17 cells in treated HIV-1-infected individuals. Mucosal Immunol. 2021;14:219-228 pubmed publisher
Karnezis T, Farnsworth R, Harris N, Williams S, Caesar C, Byrne D, et al. CCL27/CCL28-CCR10 Chemokine Signaling Mediates Migration of Lymphatic Endothelial Cells. Cancer Res. 2019;79:1558-1572 pubmed publisher
Huang G, Tao L, Shen S, Chen L. Hypoxia induced CCL28 promotes angiogenesis in lung adenocarcinoma by targeting CCR3 on endothelial cells. Sci Rep. 2016;6:27152 pubmed publisher
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher
Pacheco Rodriguez G, Kumaki F, Steagall W, Zhang Y, Ikeda Y, Lin J, et al. Chemokine-enhanced chemotaxis of lymphangioleiomyomatosis cells with mutations in the tumor suppressor TSC2 gene. J Immunol. 2009;182:1270-7 pubmed
Nakayama T, Shirane J, Hieshima K, Shibano M, Watanabe M, Jin Z, et al. Novel antiviral activity of chemokines. Virology. 2006;350:484-92 pubmed
Hieshima K, Ohtani H, Shibano M, Izawa D, Nakayama T, Kawasaki Y, et al. CCL28 has dual roles in mucosal immunity as a chemokine with broad-spectrum antimicrobial activity. J Immunol. 2003;170:1452-61 pubmed
Huber T, Reinhardt H, Exner M, Burger J, Kerjaschki D, Saleem M, et al. Expression of functional CCR and CXCR chemokine receptors in podocytes. J Immunol. 2002;168:6244-52 pubmed

image

image 1 :

Recombinant Human CCL28 Protein Bioactivity

product information

brand :

R&D Systems

master code :

717-VC

SKU :

717-VC-025

product name :

Recombinant Human CCL28 Protein

description :

The Recombinant Human CCL28 Protein from R&D Systems is derived from E. coli. The Recombinant Human CCL28 Protein has been validated for the following applications: Bioactivity.

target :

CCL28

category :

Proteins and Enzymes

unit sizes :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

theoretical molecular weight :

12 kDa

gene symbol :

CCL28

details of functionality :

Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CCR10. The ED50 for this effect is 0.4-2.0 µg/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q9NRJ3

applications :

Bioactivity

source :

E. coli-derived Recombinant Human CCL28 Protein

USD :

269 USD

alt names :

CCL28, chemokine (C-C motif) ligand 28, MEC, member 28, MGC71902, Protein CCK1, VIC

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage