product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse SIRP alpha/CD172a Fc Chimera Protein, CF
catalog :
7154-SA-050
quantity :
50 ug
price :
468 USD
more info or order :
citations: 1
Reference
Engelbertsen D, Autio A, Verwilligen R, Depuydt M, Newton G, Rattik S, et al. Increased lymphocyte activation and atherosclerosis in CD47-deficient mice. Sci Rep. 2019;9:10608 pubmed publisher
image
image 1 :
R&D Systems 7154-SA-050 image 1
Recombinant Mouse SIRP alpha/CD172a Fc Chimera Protein Bioactivity
product information
brand :
R&D Systems, a Bio-Techne brand
catalog number base :
7154-SA
SKU :
7154-SA-050
product name :
Recombinant Mouse SIRP alpha/CD172a Fc Chimera Protein, CF
description :
The Recombinant Mouse SIRP alpha/CD172a Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse SIRP alpha/CD172a Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
SIRP alpha/CD172a
unit size :
50 ug
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Mouse
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
observed molecular weight :
115-125 kDa, reducing conditions
theoretical molecular weight :
65.1 kDa (monomer)
gene symbol :
Sirpa
details of functionality :
Measured by the ability of the immobilized protein to support the adhesion of mouse red blood cells. The ED50 for this effect is 0.4-1.6 µg/mL. . Optimal dilutions should be determined by each laboratory for each application.
endotoxin note :
<1.0 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P97797
applications :
Bioactivity
product keywords :
7154-SA, rmSIRPa Fc, mSIRPa, carrier-free, carrier free, 7154SA, immunechecktargets, SIRP , SIRP alfa, SIRPa, SIRPalpha, SIRPa, SIRP-alpha, IGSF, P84, SHPS-1, SIRPalpha1, SIRPalpha2, MFR, SIRP-ALPHA-1, SHPS 1, CD47Pathway
source :
NS0-derived Recombinant Mouse SIRP alpha/CD172a Fc Chimera Protein, CF
USD :
458
USD 2025 :
468 USD
alt names :
Bit, BITbrain-immunoglobulin-like molecule with tyrosine-based activation motifs, Brain Ig-like molecule with tyrosine-based activation motifs, CD172 antigen-like family member A, CD172a, CD172a antigen, Inhibitory receptor SHPS-1, Macrophage fusion receptor, MFR, MFRtyrosine phosphatase SHP substrate 1, MYD1, MYD-1, MyD-1 antigen, P84, protein tyrosine phosphatase, non-receptor type substrate 1, PTPNS1, SHP substrate 1, SHPS1, SHPS-1, SHPS1CD172A, signal-regulatory protein alpha, Signal-regulatory protein alpha-1, Signal-regulatory protein alpha-2, Signal-regulatory protein alpha-3, SIRPA, SIRPalpha, SIRP-ALPHA-1, Sirp-alpha-2, SIRPalpha2, Sirp-alpha-3, SIRPtyrosine-protein phosphatase non-receptor type substrate 1
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.