Recombinant Mouse R-Spondin 1 (CHO-expressed) Protein, CF | R&D Systems 7150-RS-025/CF product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse R-Spondin 1 (CHO-expressed) Protein, CF

catalog :

7150-RS-025/CF

quantity :

25 ug (also 10 ug, 50 ug, 250 ug)

price :

263 USD

more info or order :

R&D Systems product webpage

citations: 9

Reference
Hiroto A, Kim W, Pineda A, He Y, Lee D, Le V, et al. Stromal androgen signaling acts as tumor niches to drive prostatic basal epithelial progenitor-initiated oncogenesis. Nat Commun. 2022;13:6552 pubmed publisher
Fu Z, Dean J, Xiong L, Dougherty M, Oliff K, Chen Z, et al. Mitochondrial transcription factor A in RORγt+ lymphocytes regulate small intestine homeostasis and metabolism. Nat Commun. 2021;12:4462 pubmed publisher
Dunbar K, Valanciute A, Lima A, Vinuela P, Jamieson T, Rajasekaran V, et al. Aspirin Rescues Wnt-Driven Stem-like Phenotype in Human Intestinal Organoids and Increases the Wnt Antagonist Dickkopf-1. Cell Mol Gastroenterol Hepatol. 2021;11:465-489 pubmed publisher
Dougherty M, Kudin O, Muhlbauer M, Neu J, Gharaibeh R, Jobin C. Gut microbiota maturation during early human life induces enterocyte proliferation via microbial metabolites. BMC Microbiol. 2020;20:205 pubmed publisher
Cai Y, Zhu G, Liu S, Pan Z, Quintero M, Poole C, et al. Indispensable role of the Ubiquitin-fold modifier 1-specific E3 ligase in maintaining intestinal homeostasis and controlling gut inflammation. Cell Discov. 2019;5:7 pubmed publisher
Eriguchi Y, Nakamura K, Yokoi Y, Sugimoto R, Takahashi S, Hashimoto D, et al. Essential role of IFN-γ in T cell-associated intestinal inflammation. JCI Insight. 2018;3: pubmed publisher
Greicius G, Kabiri Z, Sigmundsson K, Liang C, Bunte R, Singh M, et al. PDGFR?+ pericryptal stromal cells are the critical source of Wnts and RSPO3 for murine intestinal stem cells in vivo. Proc Natl Acad Sci U S A. 2018;115:E3173-E3181 pubmed publisher
Yin X, Yi H, Wang L, Wu W, Wu X, Yu L. RSPOs facilitated HSC activation and promoted hepatic fibrogenesis. Oncotarget. 2016;7:63767-63778 pubmed publisher
Fernandez Vallone V, Leprovots M, Strollo S, Vasile G, Lefort A, Libert F, et al. Trop2 marks transient gastric fetal epithelium and adult regenerating cells after epithelial damage. Development. 2016;143:1452-63 pubmed publisher

image

image 1 :

Recombinant Mouse R-Spondin 1 (CHO-expressed) Protein Bioactivity

product information

brand :

R&D Systems

master code :

7150-RS/CF

SKU :

7150-RS-025/CF

product name :

Recombinant Mouse R-Spondin 1 (CHO-expressed) Protein, CF

description :

The Recombinant Mouse R-Spondin 1 (CHO-expressed) Protein, CF from R&D Systems is derived from CHO. The Recombinant Mouse R-Spondin 1 (CHO-expressed) Protein, CF has been validated for the following applications: Bioactivity.

target :

R-Spondin 1

category :

Proteins and Enzymes

unit sizes :

25 ug (also 10 ug, 50 ug, 250 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS. *1 mg pack size (01M) is supplied as a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Mouse

observed molecular weight :

40-43 kDa, reducing conditions

theoretical molecular weight :

27 kDa

gene symbol :

Rspo1

details of functionality :

Measured by its ability to induce Topflash reporter activity in HEK293T human embryonic kidney cells. The typical ED50 is 8-40 ng/mL in the presence of 5 ng/mL Recombinant Mouse Wnt-3a (Catalog # 1324-WN ).

endotoxin note :

<0.01 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

NP_619624

applications :

Bioactivity

source :

CHO-derived Recombinant Mouse R-Spondin 1 (CHO-expressed) Protein, CF

USD :

263 USD

alt names :

Cristin 3, CRISTIN3, FLJ40906Roof plate-specific spondin-1, hRspo1, roof plate-specific spondin, RSPO, RSPO1, RSPONDIN, RSpondin 1, R-spondin homolog (Xenopus laevis), R-spondin1, R-spondin-1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage