This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Integrin alpha 2b beta 3 Protein, CF
catalog :
7148-A2
quantity :
25 ug
price :
389 USD
citations: 3
Reference
Bhatnagar S, Khera E, Liao J, Eniola V, Hu Y, Smith D, et al. Oral and Subcutaneous Administration of a Near-Infrared Fluorescent Molecular Imaging Agent Detects Inflammation in a Mouse Model of Rheumatoid Arthritis. Sci Rep. 2019;9:4661 pubmed publisher
Koh K, Cao Y, Mangos S, Tardi N, Dande R, Lee H, et al. Nonimmune cell-derived ICOS ligand functions as a renoprotective αvβ3 integrin-selective antagonist. J Clin Invest. 2019;129:1713-1726 pubmed publisher
Kwon I, Hong S, Kim Y, Nam H, Kang S, Yang S, et al. Thrombolytic effects of the snake venom disintegrin saxatilin determined by novel assessment methods: a FeCl3-induced thrombosis model in mice. PLoS ONE. 2013;8:e81165 pubmed publisher
product information
brand :
R&D Systems
master code :
7148-A2
SKU :
7148-A2-025
product name :
Recombinant Human Integrin alpha 2b beta 3 Protein, CF
description :
The Recombinant Human Integrin alpha 2b beta 3 Protein, CF from R&D Systems is derived from CHO. The Recombinant Human Integrin alpha 2b beta 3 Protein, CF has been validated for the following applications: Bioactivity.
target :
Integrin alpha 2b beta 3
category :
Proteins and Enzymes
unit size :
25 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Human
observed molecular weight :
140-150 kDa 110-120 kDa, reducing conditions
theoretical molecular weight :
113.6 kDa (Integrin alpha 2b) 84.8 kDa (Integrin beta 3)
gene symbol :
ITGA2B
details of functionality :
Measured by its binding ability in a functional ELISA. When Recombinant Human Integrin alpha 2b beta 3 is coated at 2 µg/mL, Human Fibronectin (Catalog # 1918-FN ) binds with an apparent Kd 1 nM.
endotoxin note :
<1.0 EU per 1 µg of the protein by the LAL method.
catalog number base :
7148-A2
accessionNumbers :
P08514 (Integrin alpha 2b) AAA52589 (Integrin beta 3)
applications :
Bioactivity
source :
Chinese Hamster Ovary cell line, CHO-derived human Integrin alpha 2b beta 3 protein Human Integrin alpha 2b Met1-Arg993 (R887L) Accession # P08514 GGGSGGGSGGGS Acidic Tail HHHHHH Human Integrin beta 3 (Gly27-Asp718) Accession # AAA52589 HP GGGSGGGSGGGS Basic Tail N-terminus C-terminus
2020 USD :
389
2021 USD :
389 USD
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.