Recombinant Human Integrin alpha 2b beta 3 Protein, CF | R&D Systems 7148-A2-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Integrin alpha 2b beta 3 Protein, CF

catalog :

7148-A2-025

quantity :

25 ug

price :

481 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Bhatnagar S, Khera E, Liao J, Eniola V, Hu Y, Smith D, et al. Oral and Subcutaneous Administration of a Near-Infrared Fluorescent Molecular Imaging Agent Detects Inflammation in a Mouse Model of Rheumatoid Arthritis. Sci Rep. 2019;9:4661 pubmed publisher
Koh K, Cao Y, Mangos S, Tardi N, Dande R, Lee H, et al. Nonimmune cell-derived ICOS ligand functions as a renoprotective αvβ3 integrin-selective antagonist. J Clin Invest. 2019;129:1713-1726 pubmed publisher
Kwon I, Hong S, Kim Y, Nam H, Kang S, Yang S, et al. Thrombolytic effects of the snake venom disintegrin saxatilin determined by novel assessment methods: a FeCl3-induced thrombosis model in mice. PLoS ONE. 2013;8:e81165 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

7148-A2

SKU :

7148-A2-025

product name :

Recombinant Human Integrin alpha 2b beta 3 Protein, CF

Description :

The Recombinant Human Integrin alpha 2b beta 3 Protein, CF from R&D Systems is derived from CHO. The Recombinant Human Integrin alpha 2b beta 3 Protein, CF has been validated for the following applications: Bioactivity.

target :

Integrin alpha 2b beta 3

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

140-150 kDa 110-120 kDa, reducing conditions

theoretical molecular weight :

113.6 kDa (Integrin alpha 2b) 84.8 kDa (Integrin beta 3)

gene symbol :

ITGA2B

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Human Integrin alpha 2b beta 3 is coated at 2 µg/mL, Human Fibronectin (Catalog # 1918-FN ) binds with an apparent Kd 1 nM.

endotoxin note :

<1.0 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P08514 (Integrin alpha 2b) AAA52589 (Integrin beta 3)

applications :

Bioactivity

source :

CHO-derived Recombinant Human Integrin alpha 2b beta 3 Protein

USD :

481 USD

alt names :

BDPLT16;BDPLT2;CD41;CD41B;GP2B;GPIIb;GT;GT1;GTA;HPA3;Integrin alpha-IIb;ITGA2B;PPP1R93

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage