Recombinant Human EphA1 Fc Chimera Protein, CF | R&D Systems 7146-A1-100 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human EphA1 Fc Chimera Protein, CF

catalog :

7146-A1-100

quantity :

100 ug

price :

348 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Cha J, Chan L, Wang Y, Chu Y, Wang C, Lee H, et al. Ephrin receptor A10 monoclonal antibodies and the derived chimeric antigen receptor T cells exert an antitumor response in mouse models of triple-negative breast cancer. J Biol Chem. 2022;298:101817 pubmed publisher
Ieguchi K, Tomita T, Omori T, Komatsu A, Deguchi A, Masuda J, et al. ADAM12-cleaved ephrin-A1 contributes to lung metastasis. Oncogene. 2014;33:2179-90 pubmed publisher

product information

master code :

7146-A1

SKU :

7146-A1-100

product name :

Recombinant Human EphA1 Fc Chimera Protein, CF

unit size :

100 ug

description :

The Recombinant Human EphA1 Fc Chimera Protein, CF from R&D Systems is derived from HEK293. The Recombinant Human EphA1 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

EphA1

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in MES, NaCl, PEG 3350, CHAPS and Imidazole.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

100-110 kDa, reducing conditions

theoretical molecular weight :

83.5 kDa (monomer)

gene symbol :

EPHA1

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Human EphA1 Fc Chimera is coated at 2 ╡g/mL (100 ╡L/well), the concentration of Biotinylayed Recombinant Mouse Ephrin-A1 Fc Chimera (Catalog # BT602 ) that produces 50% of the optimal binding response is typically 10-50 ng/mL.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

AAA36747

applications :

Bioactivity

source long :

Human embryonic kidney cell, HEK293-derived human EphA1 protein Human EphA1 (Met1-Glu547) Accession # AAA36747 DIEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus

source short :

HEK293

USD :

348 USD

alt names :

EC 2.7.10, EC 2.7.10.1, EPH receptor A1, eph tyrosine kinase 1, EphA1, EPHephrin type-A receptor 1, EPHT, EPHT1erythropoietin-producing hepatoma amplified sequence, Esk, MGC163163, oncogene EPH, soluble EPHA1 variant 1, soluble EPHA1 variant 2, Tyrosine-protein kinase receptor EPH

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after opening. 3 months, -20 to -70 ░C under sterile conditions after opening.

more info or order :

R&D Systems product webpage