Recombinant Human BMP-2/BMP-6 Heterodimer Protein | R&D Systems 7145-BP-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human BMP-2/BMP-6 Heterodimer Protein

catalog :

7145-BP-010

quantity :

10 ug

price :

643 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Srole D, Jung G, Waring A, Nemeth E, Ganz T. Characterization of erythroferrone structural domains relevant to its iron-regulatory function. J Biol Chem. 2023;299:105374 pubmed publisher
Krouwels A, Iljas J, Kragten A, Dhert W, Oner F, Tryfonidou M, et al. Bone Morphogenetic Proteins for Nucleus Pulposus Regeneration. Int J Mol Sci. 2020;21: pubmed publisher
Toyoda E, Sato M, Takahashi T, Maehara M, Nakamura Y, Mitani G, et al. Multilineage-differentiating stress-enduring (Muse)-like cells exist in synovial tissue. Regen Ther. 2019;10:17-26 pubmed publisher
Loozen L, Vandersteen A, Kragten A, Oner F, Dhert W, Kruyt M, et al. Bone formation by heterodimers through non-viral gene delivery of BMP-2/6 and BMP-2/7. Eur Cell Mater. 2018;35:195-208 pubmed publisher

product information

master code :

7145-BP

SKU :

7145-BP-010

product name :

Recombinant Human BMP-2/BMP-6 Heterodimer Protein

unit size :

10 ug

description :

The Recombinant Human BMP-2/BMP-6 Heterodimer Protein from R&D Systems is derived from E. coli. The Recombinant Human BMP-2/BMP-6 Heterodimer Protein has been validated for the following applications: Bioactivity.

target :

BMP-2/BMP-6 Heterodimer

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in HCl with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

11 kDa 14 kDa, reducing conditions

theoretical molecular weight :

12.8 kDa (BMP-2) 15 kDa (BMP-6)

gene symbol :

BMP2

details of functionality :

Measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells. Binnerts, M.E. et al . (2004) Biochem. Biophys. Res. Commun. 315(2) :272. The ED50 for this effect is 4-20 ng/mL.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P12643 (BMP-2) P22004 (BMP-6)

applications :

Bioactivity

source long :

E. coli -derived human BMP-2/BMP-6 Heterodimer protein Human BMP-2 (Ala284 - Arg396), with an N-terminal Met Accession # P12643 Human BMP-6 (Gln382 - His513), with an N-terminal Met Accession # P22004 N-terminus C-terminus

source short :

E. coli

USD :

643 USD

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage