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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human VISTA/B7-H5/PD-1H Fc Chimera Protein, CF
catalog :
7126-B7-050
quantity :
50 ug (also 1 mg)
price :
434 USD
more info or order :
citations: 1
Reference
Wang J, Wu G, Manick B, Hernandez V, Renelt M, Erickson C, et al. VSIG-3 as a ligand of VISTA inhibits human T-cell function. Immunology. 2019;156:74-85 pubmed publisher
image
image 1 :
R&D Systems 7126-B7-050 image 1
Recombinant Human VISTA/B7-H5/PD-1H Fc Chimera Protein Bioactivity
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
7126-B7
SKU :
7126-B7-050
product name :
Recombinant Human VISTA/B7-H5/PD-1H Fc Chimera Protein, CF
Description :
The Recombinant Human VISTA/B7-H5/PD-1H Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human VISTA/B7-H5/PD-1H Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
VISTA/B7-H5/PD-1H
category :
Proteins and Enzymes
unit size :
50 ug (also 1 mg)
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Human
observed molecular weight :
64-75 kDa, reducing conditions
theoretical molecular weight :
44.8 kDa (monomer)
gene symbol :
C10orf54
details of functionality :
Measured by its ability to inhibit anti-CD3 antibody induced IL-2 secretion in human T lymphocytes. The ED50 for this effect is 1-6 µg/mL.
endotoxin note :
<0.01 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
AAH20568
applications :
Bioactivity
source :
NS0-derived Recombinant Human VISTA/B7-H5/PD-1H Fc Chimera Protein
USD :
434 USD
alt names :
4632428N05Rik, B7H5, B7-H5, C10orf54, chromosome 10 open reading frame 54, Dies1, Gi24, PD1H, PD-1H, platelet receptor Gi24, PP2135, SISP1, stress induced secreted protein 1, VSIR
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.