Recombinant Human FGFR2 alpha (IIIc) Fc Chimera Protein, CF | R&D Systems 712-FR-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human FGFR2 alpha (IIIc) Fc Chimera Protein, CF

catalog :

712-FR-050

quantity :

50 ug

price :

407 USD

more info or order :

R&D Systems product webpage

citations: 1

Reference
Yanucil C, Kentrup D, Li X, Grabner A, Schramm K, Martinez E, et al. FGF21-FGFR4 signaling in cardiac myocytes promotes concentric cardiac hypertrophy in mouse models of diabetes. Sci Rep. 2022;12:7326 pubmed publisher

product information

master code :

712-FR

SKU :

712-FR-050

product name :

Recombinant Human FGFR2 alpha (IIIc) Fc Chimera Protein, CF

unit size :

50 ug

description :

The Recombinant Human FGFR2 alpha (IIIc) Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human FGFR2 alpha (IIIc) Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

FGFR2 alpha

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

100-110 kDa, reducing conditions

theoretical molecular weight :

66 kDa (monomer)

gene symbol :

FGFR2

details of functionality :

Measured by its ability to inhibit FGF acidic-dependent proliferation of NR6R-3T3 mouse fibroblast cells. The ED50 for this effect is 0.5-2áng/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P21802

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived human FGF R2 alpha protein Human FGF R2 alpha (IIIc) (Arg22 - Glu377) (Leu27 - Glu377) Accession # P21802 IEGRMD Human IgG1 (Pro100 - Lys330) N-terminus C-terminus

source short :

NS0

USD :

407 USD

alt names :

BBDS;BEK;BFR-1;CD332;CEK3;CFD1;ECT1;Fibroblast growth factor receptor;Fibroblast growth factor receptor 2;JWS;KGFR;K-SAM;Receptor protein-tyrosine kinase;TK14;TK25, CD332, FGF R2, FGF R2a

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage