product summary
Loading...
company name :
R&D Systems
product type :
protein
product name :
Recombinant Porcine GM-CSF Protein
catalog :
711-PG-010
quantity :
10 ug
price :
351 USD
more info or order :
R&D Systems product webpage
citations: 20
Reference
Zheng L, Zhao F, Ru J, Liu L, Wang Z, Wang N, et al. Evaluation of the Effect of Inactivated Transmissible Gastroenteritis Virus Vaccine with Nano Silicon on the Phenotype and Function of Porcine Dendritic Cells. Viruses. 2021;13: pubmed publisher
Hamid B, Schlosser Brandenburg J, Bechtold L, Ebner F, Rausch S, Hartmann S. Early Immune Initiation by Porcine Cells following Toxoplasma gondii Infection versus TLR Ligation. Microorganisms. 2021;9: pubmed publisher
Qu X, Neuhoff C, Cinar M, Pröll M, Tholen E, Tesfaye D, et al. Epigenetic Modulation of TLR4 Expression by Sulforaphane Increases Anti-Inflammatory Capacity in Porcine Monocyte-Derived Dendritic Cells. Biology (Basel). 2021;10: pubmed publisher
Zheng D, Wang Z, Sui L, Xu Y, Wang L, Qiao X, et al. Lactobacillus johnsonii activates porcine monocyte derived dendritic cells maturation to modulate Th cellular immune response. Cytokine. 2021;144:155581 pubmed publisher
Geervliet M, Lute L, Jansen C, Rutten V, Savelkoul H, Tijhaar E. Differential immunomodulation of porcine bone marrow derived dendritic cells by E. coli Nissle 1917 and β-glucans. PLoS ONE. 2020;15:e0233773 pubmed publisher
Zhou L, Wang L, Zhao W, Ren S, Tu F, Fu Y, et al. Transcriptome sequencing analysis of porcine MDM response to FSL-1 stimulation. Microb Pathog. 2020;138:103830 pubmed publisher
Kim S, Hwang J, Kim Y, Lee H. Heterogeneity of porcine bone marrow-derived dendritic cells induced by GM-CSF. PLoS ONE. 2019;14:e0223590 pubmed publisher
Li Y, Darwich L, Mateu E. Characterization of the attachment and infection by Porcine reproductive and respiratory syndrome virus 1 isolates in bone marrow-derived dendritic cells. Vet Microbiol. 2018;223:181-188 pubmed publisher
Franzoni G, Graham S, Sanna G, Angioi P, Fiori M, Anfossi A, et al. Interaction of porcine monocyte-derived dendritic cells with African swine fever viruses of diverse virulence. Vet Microbiol. 2018;216:190-197 pubmed publisher
Singleton H, Graham S, Frossard J, Bodman Smith K, Steinbach F. Infection of monocytes with European porcine reproductive and respiratory syndrome virus (PRRSV-1) strain Lena is significantly enhanced by dexamethasone and IL-10. Virology. 2018;517:199-207 pubmed publisher
Ahlberg V, Hjertner B, Wallgren P, Hellman S, Lövgren Bengtsson K, Fossum C. Innate immune responses induced by the saponin adjuvant Matrix-M in specific pathogen free pigs. Vet Res. 2017;48:30 pubmed publisher
Martelet L, Lacouture S, Goyette Desjardins G, Beauchamp G, Surprenant C, Gottschalk M, et al. Porcine Dendritic Cells as an In Vitro Model to Assess the Immunological Behaviour of Streptococcus suis Subunit Vaccine Formulations and the Polarizing Effect of Adjuvants. Pathogens. 2017;6: pubmed publisher
Nedumpun T, Ritprajak P, Suradhat S. Generation of potent porcine monocyte-derived dendritic cells (MoDCs) by modified culture protocol. Vet Immunol Immunopathol. 2016;182:63-68 pubmed publisher
Fan B, Liu X, Bai J, Li Y, Zhang Q, Jiang P. The 15N and 46R Residues of Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus Nucleocapsid Protein Enhance Regulatory T Lymphocytes Proliferation. PLoS ONE. 2015;10:e0138772 pubmed publisher
Rodríguez Gómez I, Käser T, Gómez Laguna J, Lamp B, Sinn L, Rümenapf T, et al. PRRSV-infected monocyte-derived dendritic cells express high levels of SLA-DR and CD80/86 but do not stimulate PRRSV-naïve regulatory T cells to proliferate. Vet Res. 2015;46:54 pubmed publisher
Qu X, Pröll M, Neuhoff C, Zhang R, Cinar M, Hossain M, et al. Sulforaphane epigenetically regulates innate immune responses of porcine monocyte-derived dendritic cells induced with lipopolysaccharide. PLoS ONE. 2015;10:e0121574 pubmed publisher
Crisci E, Fraile L, Novellas R, Espada Y, Cabezón R, Martínez J, et al. In vivo tracking and immunological properties of pulsed porcine monocyte-derived dendritic cells. Mol Immunol. 2015;63:343-54 pubmed publisher
Kyrova K, Stepanova H, Rychlik I, Polansky O, Leva L, Sekelova Z, et al. The response of porcine monocyte derived macrophages and dendritic cells to Salmonella Typhimurium and lipopolysaccharide. BMC Vet Res. 2014;10:244 pubmed publisher
Jeong W, Kim J, Bazer F, Song G. Proliferation-stimulating effect of colony stimulating factor 2 on porcine trophectoderm cells is mediated by activation of phosphatidylinositol 3-kinase and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase. PLoS ONE. 2014;9:e88731 pubmed publisher
Tambuyzer B, Nouwen E. Inhibition of microglia multinucleated giant cell formation and induction of differentiation by GM-CSF using a porcine in vitro model. Cytokine. 2005;31:270-9 pubmed
product information
brand :
R&D Systems
master code :
711-PG
SKU :
711-PG-010
product name :
Recombinant Porcine GM-CSF Protein
description :
The Recombinant Porcine GM-CSF Protein from R&D Systems is derived from E. coli. The Recombinant Porcine GM-CSF Protein has been validated for the following applications: Bioactivity.
target :
GM-CSF
category :
Proteins and Enzymes
unit sizes :
10 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Porcine
theoretical molecular weight :
14.4 kDa
gene symbol :
CSF2
details of functionality :
Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. Kitamura, T. et al . (1989) J. Cell Physiol. 140 :323. The ED50 for this effect is typically 0.6-3.8 ng/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
Q29118
applications :
Bioactivity
source :
E. coli-derived Recombinant Porcine GM-CSF Protein
USD :
351 USD
alt names :
colony stimulating factor 2 (granulocyte-macrophage), Colony-stimulating factor, CSF, CSF2, CSF-2, GMCSF, GM-CSF, GMCSFgranulocyte-macrophage colony-stimulating factor, granulocyte-macrophage colony stimulating factor, MGC131935, MGC138897, Molgramostim, molgramostin, sargramostim
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.