product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse FGFR2 beta (IIIb) Fc Chimera Protein, CF
catalog :
708-MF-050
quantity :
50 ug
price :
428 USD
more info or order :
R&D Systems product webpage
citations: 5
Reference
Brownfield D, de Arce A, Ghelfi E, Gillich A, Desai T, Krasnow M. Alveolar cell fate selection and lifelong maintenance of AT2 cells by FGF signaling. Nat Commun. 2022;13:7137 pubmed publisher
Hansson M, Olesen D, Peterslund J, Engberg N, Kahn M, Winzi M, et al. A late requirement for Wnt and FGF signaling during activin-induced formation of foregut endoderm from mouse embryonic stem cells. Dev Biol. 2009;330:286-304 pubmed publisher
Yamamoto S, Fukumoto E, Yoshizaki K, Iwamoto T, Yamada A, Tanaka K, et al. Platelet-derived growth factor receptor regulates salivary gland morphogenesis via fibroblast growth factor expression. J Biol Chem. 2008;283:23139-49 pubmed publisher
Patel V, Knox S, Likar K, Lathrop C, Hossain R, Eftekhari S, et al. Heparanase cleavage of perlecan heparan sulfate modulates FGF10 activity during ex vivo submandibular gland branching morphogenesis. Development. 2007;134:4177-86 pubmed
Steinberg Z, Myers C, Heim V, Lathrop C, Rebustini I, Stewart J, et al. FGFR2b signaling regulates ex vivo submandibular gland epithelial cell proliferation and branching morphogenesis. Development. 2005;132:1223-34 pubmed
product information
brand :
R&D Systems
master code :
708-MF
SKU :
708-MF-050
product name :
Recombinant Mouse FGFR2 beta (IIIb) Fc Chimera Protein, CF
description :
The Recombinant Mouse FGFR2 beta (IIIb) Fc Chimera Protein, CF from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Mouse FGFR2 beta (IIIb) Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
FGFR2 beta
category :
Proteins and Enzymes
unit sizes :
50 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Mouse
observed molecular weight :
74 kDa, reducing conditions
theoretical molecular weight :
56 kDa (monomer)
gene symbol :
Fgfr2
details of functionality :
Measured by its ability to inhibit FGF acidic-dependent proliferation of NR6R-3T3 mouse fibroblast cells. The ED50 for this effect is 0.5-2 ng/mL.
endotoxin note :
<1.0 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
AAI72174
applications :
Bioactivity
source :
Sf 21 (baculovirus)-derived Recombinant Mouse FGFR2 beta (IIIb) Fc Chimera Protein, CF
USD :
428 USD
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.