Recombinant Human Neuroligin 1v2/NLGN1v2 Protein, CF | R&D Systems 7066-NL-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Neuroligin 1v2/NLGN1v2 Protein, CF

catalog :

7066-NL-050

quantity :

50 ug

price :

468 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Voss A, Lanjewar S, Sampson M, King A, Hill E, Sing A, et al. Identification of ligand-receptor pairs that drive human astrocyte development. Nat Neurosci. 2023;26:1339-1351 pubmed publisher
Camporesi E, Lashley T, Gobom J, Lantero Rodriguez J, Hansson O, Zetterberg H, et al. Neuroligin-1 in brain and CSF of neurodegenerative disorders: investigation for synaptic biomarkers. Acta Neuropathol Commun. 2021;9:19 pubmed publisher
Venkatesh H, Tam L, Woo P, Lennon J, Nagaraja S, Gillespie S, et al. Targeting neuronal activity-regulated neuroligin-3 dependency in high-grade glioma. Nature. 2017;549:533-537 pubmed publisher

product information

master code :

7066-NL

SKU :

7066-NL-050

product name :

Recombinant Human Neuroligin 1v2/NLGN1v2 Protein, CF

unit size :

50 ug

description :

The Recombinant Human Neuroligin 1v2/NLGN1v2 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Neuroligin 1v2/NLGN1v2 Protein, CF has been validated for the following applications: Bioactivity.

target :

Neuroligin 1/NLGN1

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

90-110 kDa, reducing conditions

theoretical molecular weight :

71.3 kDa

gene symbol :

NLGN1

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Human Neuroligin 1/NLGN1 Variant 2 is immobilized at 5.0 ╡g/mL, Recombinant Human Neurexin 1▀ Fc Chimera (Catalog # 5268-NX) binds with an apparent KD 30 nM.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_055747

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived human Neuroligin 1/NLGN1 protein Met1-Ser677, with a C-terminal 6-His tag

source short :

NS0

USD :

468 USD

alt names :

EC 3.1.1, EC 3.1.1.1, KIAA1070neuroligin-1, MGC45115, neuroligin 1, NL1, Nlg, NLGN1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage