product summary
Loading...
company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse IL-36 beta/IL-1F8 (aa 31-183) Protein, CF
catalog :
7060-ML-010/CF
quantity :
10 ug
price :
432 USD
more info or order :
R&D Systems product webpage
citations: 1
Reference
Tortola L, Rosenwald E, Abel B, Blumberg H, Schafer M, Coyle A, et al. Psoriasiform dermatitis is driven by IL-36-mediated DC-keratinocyte crosstalk. J Clin Invest. 2012;122:3965-76 pubmed publisher
product information
master code :
7060-ML/CF
SKU :
7060-ML-010/CF
product name :
Recombinant Mouse IL-36 beta/IL-1F8 (aa 31-183) Protein, CF
unit size :
10 ug
description :
The Recombinant Mouse IL-36 beta/IL-1F8 (aa 31-183) Protein, CF from R&D Systems is derived from E. coli. The Recombinant Mouse IL-36 beta/IL-1F8 (aa 31-183) Protein, CF has been validated for the following applications: Bioactivity.
target :
IL-36 beta/IL-1F8
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in MES, NaCl, TCEP, EDTA, CHAPS and PEG 8000 with Trehalose.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Mouse
observed molecular weight :
16 kDa, reducing conditions
theoretical molecular weight :
17.4 kDa
gene symbol :
Il1f8
details of functionality :
Measured by its ability to induce IL-6 secretion by NIH-3T3 mouse embryonic fibroblast cells. Towne, J.E. et al . (2004) J. Biol. Chem. 279 :13677. The ED50 for this effect is 1-6 ng/mL.
endotoxin note :
<0.01 EU per 1 ╡g of the protein by the LAL method.
top caption :
Recombinant Mouse IL-36 beta/IL-1F8 (aa 31-183) Protein Bioactivity
accessionNumbers :
Q9D6Z6
applications :
Bioactivity
source long :
E. coli -derived mouse IL-36 beta/IL-1F8 protein Ser31-Lys183
source short :
E. coli
USD :
432 USD
alt names :
family of interleukin 1-eta, FIL1, FIL1 eta, FIL1-(ETA), FIL1H, FILI-(ETA), IL-1 eta, IL1-ETA, IL1F8, IL-1F8, IL1F8 (Canonical product IL-1F8a), IL-1F8 (FIL1-eta), IL1H2, IL-1H2, IL36 beta, IL36B, interleukin 1 family, member 8 (eta), interleukin 1, eta, Interleukin 36, Beta, Interleukin-1 eta, interleukin-1 family member 8, Interleukin-1 homolog 2, Interleukin-1 Superfamily e, Interleukin-36 Beta
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.