Recombinant Human Caspase-8 Protein, CF | R&D Systems 705-C8-010/CF product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Caspase-8 Protein, CF

catalog :

705-C8-010/CF

quantity :

10 ug

price :

480 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Yun N, Lee Y, Kim C, Shibayama H, Tanimura A, Hamanaka Y, et al. Anamorsin, a novel caspase-3 substrate in neurodegeneration. J Biol Chem. 2014;289:22183-95 pubmed publisher
Guery L, Benikhlef N, Gautier T, Paul C, Jego G, Dufour E, et al. Fine-tuning nucleophosmin in macrophage differentiation and activation. Blood. 2011;118:4694-704 pubmed publisher

product information

master code :

705-C8/CF

SKU :

705-C8-010/CF

product name :

Recombinant Human Caspase-8 Protein, CF

unit size :

10 ug

description :

The Recombinant Human Caspase-8 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human Caspase-8 Protein, CF has been validated for the following applications: Enzyme Activity.

target :

Caspase-8

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in HEPES, NaCl, DTT and Sucrose.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

18 kDa and 10 kDa, reducing conditions

theoretical molecular weight :

18 kDa 10 kDa

gene symbol :

CASP8

details of functionality :

Measured by its ability to cleave a fluorogenic peptide substrate Ac-IETD-AFC. The specific activity is 1,000 pmol/min/╡g, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q14790

applications :

Enzyme Activity

source long :

E. coli -derived human Caspase-8 protein Ser217-Asp384 (Asp285His) (p18 subunit) & Leu385-Asp479 (p10 subunit), with a C-terminal 6-His tag

source short :

E. coli

USD :

480 USD

alt names :

AIS, androgen receptor, CASP8, Caspase8, DHTRTFM, Dihydrotestosterone receptorHYSP1, HUMARA, Mch5, NR3C4KD, Nuclear receptor subfamily 3 group C member 4, SMAX1SBMA, spinal and bulbar muscular atrophy

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -70 ░C as supplied. 3 months, -70 ░C under sterile conditions after opening.

more info or order :

R&D Systems product webpage