Recombinant Human Active Caspase-2 Protein, CF | R&D Systems 702-C2-010/CF product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Active Caspase-2 Protein, CF

catalog :

702-C2-010/CF

quantity :

10 ug

price :

480 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Yun N, Lee Y, Kim C, Shibayama H, Tanimura A, Hamanaka Y, et al. Anamorsin, a novel caspase-3 substrate in neurodegeneration. J Biol Chem. 2014;289:22183-95 pubmed publisher
Wejda M, Impens F, Takahashi N, Van Damme P, Gevaert K, Vandenabeele P. Degradomics reveals that cleavage specificity profiles of caspase-2 and effector caspases are alike. J Biol Chem. 2012;287:33983-95 pubmed publisher
Guery L, Benikhlef N, Gautier T, Paul C, Jego G, Dufour E, et al. Fine-tuning nucleophosmin in macrophage differentiation and activation. Blood. 2011;118:4694-704 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne brand

catalog number base :

702-C2/CF

SKU :

702-C2-010/CF

product name :

Recombinant Human Active Caspase-2 Protein, CF

description :

The Recombinant Human Active Caspase-2 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human Active Caspase-2 Protein, CF has been validated for the following applications: Enzyme Activity.

target :

Caspase-2

unit size :

10 ug

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 µm filtered solution in HEPES, NaCl, DTT and Sucrose.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -70 °C as supplied. 3 months, -70 °C under sterile conditions after opening.

observed molecular weight :

10-12 kDa 17 kDa, under reducing conditions.

theoretical molecular weight :

12 kDa 18 kDa

gene symbol :

CASP2

details of functionality :

Measured by its ability to cleave the fluorogenic peptide substrate Ac-VDVAD-AFC. The specific activity is 1000 pmol/min/µg, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P42575

applications :

Enzyme Activity

product keywords :

702-C2, rhActive Caspase-2, hCaspase-2, carrier-free, carrier free, 7O2-C2/CF, 702C2/CF, Caspase2, Caspase 2, Cysteine Protease, CASP 2

source :

E. coli-derived Recombinant Human Active Caspase-2 Protein, CF

USD :

470

USD 2025 :

480 USD

alt names :

caspase-2, CASP2, CASP-2, caspase 2, apoptosis-related cysteine peptidase, Caspase2, ICH1, ICH-1, NEDD2, NEDD-2, PPP1R57

more info or order :

R&D Systems product webpage