Recombinant Mouse R-Spondin 2 Protein, CF | R&D Systems 6946-RS-025/CF product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse R-Spondin 2 Protein, CF

catalog :

6946-RS-025/CF

quantity :

25 ug

price :

423 USD

more info or order :

R&D Systems product webpage

citations: 5

Reference
Termini C, Pang A, Fang T, Roos M, Chang V, Zhang Y, et al. Neuropilin 1 regulates bone marrow vascular regeneration and hematopoietic reconstitution. Nat Commun. 2021;12:6990 pubmed publisher
Zhang M, Haughey M, Wang N, Blease K, Kapoun A, Couto S, et al. Targeting the Wnt signaling pathway through R-spondin 3 identifies an anti-fibrosis treatment strategy for multiple organs. PLoS ONE. 2020;15:e0229445 pubmed publisher
Sah J, Hao N, Han X, Tran T, McCarthy S, Oh Y, et al. Ectonucleotide pyrophosphatase 2 (ENPP2) plays a crucial role in myogenic differentiation through the regulation by WNT/β-Catenin signaling. Int J Biochem Cell Biol. 2020;118:105661 pubmed publisher
Periasamy P, Tran V, O Neill H. Identification of genes which regulate stroma-dependent in vitro hematopoiesis. PLoS ONE. 2018;13:e0205583 pubmed publisher
Yin X, Yi H, Wang L, Wu W, Wu X, Yu L. RSPOs facilitated HSC activation and promoted hepatic fibrogenesis. Oncotarget. 2016;7:63767-63778 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

6946-RS/CF

SKU :

6946-RS-025/CF

product name :

Recombinant Mouse R-Spondin 2 Protein, CF

Description :

The Recombinant Mouse R-Spondin 2 Protein, CF from R&D Systems is derived from CHO. The Recombinant Mouse R-Spondin 2 Protein, CF has been validated for the following applications: Bioactivity.

target :

R-Spondin 2

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Mouse

observed molecular weight :

26-27 kDa, reducing conditions

theoretical molecular weight :

21 kDa 20 kDa

gene symbol :

Rspo2

details of functionality :

Measured by its ability to induce Topflash reporter activity in HEK293T human embryonic kidney cells. The ED50 for this effect is typically 0.4-2.4 ng/mL in the presence of 5 ng/mL Recombinant Mouse Wnt-3a (Catalog # 1324-WN ).

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

NP_766403

applications :

Bioactivity

source :

CHO-derived Recombinant Mouse R-Spondin 2 Protein

USD :

423 USD

alt names :

Cristin 2, CRISTIN2, hRspo2, MGC35555, MGC43342, Roof plate-specific spondin-2, RSPO2, RSpondin 2, R-spondin 2 homolog (Xenopus laevis), R-spondin-2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage