Recombinant Human GITR Ligand/TNFSF18 Protein, CF | R&D Systems 694-GL-025/CF product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human GITR Ligand/TNFSF18 Protein, CF

catalog :

694-GL-025/CF

quantity :

25 ug

price :

443 USD

citations: 4

Reference
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher
Baltz K, Krusch M, Baessler T, Schmiedel B, Bringmann A, Brossart P, et al. Neutralization of tumor-derived soluble glucocorticoid-induced TNFR-related protein ligand increases NK cell anti-tumor reactivity. Blood. 2008;112:3735-43 pubmed publisher
Bae E, Kim W, Kang Y, Suk K, Koh E, Cha H, et al. Glucocorticoid-induced tumour necrosis factor receptor-related protein-mediated macrophage stimulation may induce cellular adhesion and cytokine expression in rheumatoid arthritis. Clin Exp Immunol. 2007;148:410-8 pubmed
Mahesh S, Li Z, Liu B, Fariss R, Nussenblatt R. Expression of GITR ligand abrogates immunosuppressive function of ocular tissue and differentially modulates inflammatory cytokines and chemokines. Eur J Immunol. 2006;36:2128-38 pubmed

product information

brand :

R&D Systems, a Bio-Techne brand

catalog number base :

694-GL/CF

SKU :

694-GL-025/CF

product name :

Recombinant Human GITR Ligand/TNFSF18 Protein, CF

description :

The Recombinant Human GITR Ligand/TNFSF18 Protein, CF from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Human GITR Ligand/TNFSF18 Protein, CF has been validated for the following applications: Binding Activity.

target :

GITR Ligand/TNFSF18

unit size :

25 ug

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

observed molecular weight :

14 kDa-16 kDa, reducing conditions

theoretical molecular weight :

15 kDa

gene symbol :

TNFSF18

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Human GITR/TNFRSF18 Fc Chimera (Catalog # 689-GR ) is immobilized at 0.5 µg/mL (100 µL/well), Recombinant Human GITR Ligand/TNFSF18 binds with an ED50 of 30-300 ng/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q9UNG2

applications :

Binding Activity

product keywords :

694-GL, rhGITRL, hGITRL, carrier-free, carrier free, 694GL/CF, immunechecktargets, cytokinegrowthfact, GITR L, TNFSF 18, GITRLigand, cytokine, cytokines, TNFSFCoReg, AITRL, TNF Superfamily Member 18, HGITRL, GITRL, TL6, Tumor Necrosis Factor Ligand Superfamily Member 18, AITR Ligand, TNLG2A, Glucocorticoid-Induced TN

source :

Sf 21 (baculovirus)-derived Recombinant Human GITR Ligand/TNFSF18 Protein, CF

extended description :

A New and Improved rh GITR-L is Available! CHO expressed; ~70 fold better activity; HA tag!

USD :

434

USD 2025 :

443 USD

product details :

A New and Improved rh GITR-L is Available! CHO expressed; ~70 fold better activity; HA tag!

alt names :

Activation-inducible TNF-related ligand, AITRL, AITRLMGC138237, GITRL, GITRLglucocorticoid-induced TNFR-related protein ligand, Glucocorticoid-induced TNF-related ligand, hGITRLGITR ligand, TL6AITR ligand, TNFSF18, tumor necrosis factor (ligand) superfamily, member 18, tumor necrosis factor ligand superfamily member 18