Recombinant Human GDF-1 Protein | R&D Systems 6937-GD-010 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human GDF-1 Protein

catalog :

6937-GD-010

quantity :

10 ug

price :

528 USD

citations: 3

Reference
Alves J, SCHWINN M, Machleidt T, Goueli S, Cali J, Zegzouti H. Monitoring phosphorylation and acetylation of CRISPR-mediated HiBiT-tagged endogenous proteins. Sci Rep. 2024;14:2138 pubmed publisher
Cheng W, Li H, Xi S, Zhang X, Zhu Y, Le Xing -, et al. Growth differentiation factor 1-induced tumour plasticity provides a therapeutic window for immunotherapy in hepatocellular carcinoma. Nat Commun. 2021;12:7142 pubmed publisher
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher

product information

master code :

6937-GD

SKU :

6937-GD-010

product name :

Recombinant Human GDF-1 Protein

unit size :

10 ug

description :

The Recombinant Human GDF-1 Protein from R&D Systems is derived from CHO. The Recombinant Human GDF-1 Protein has been validated for the following applications: Bioactivity.

target :

GDF-1

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in HCl with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

13 kDa, reducing conditions

theoretical molecular weight :

12.6 kDa (monomer)

gene symbol :

GDF1

details of functionality :

Measured by its ability to induce Smad2 phosphorylation in P19 mouse embryonal carcinoma cells. Mazerbourg, S. et al . (2004) Mol. Endocrinol. 18 :653. 50 ng/mL of Recombinant Human GDF-1 can effectively induce Smad2 phosphorylation.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_001483

applications :

Bioactivity

source long :

Chinese Hamster Ovary cell line, CHO-derived human GDF-1 protein Asp254-Arg372

source short :

CHO

USD :

528 USD

alt names :

DORV, DTGA3, embryonic growth/differentiation factor 1, GDF1, GDF-1, growth differentiation factor 1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.