Recombinant Human Cerebellin-1 Protein, CF | R&D Systems 6934-CB-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Cerebellin-1 Protein, CF

catalog :

6934-CB-025

quantity :

25 ug

price :

552 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Han P, She Y, Yang Z, Zhuang M, Wang Q, Luo X, et al. Cbln1 regulates axon growth and guidance in multiple neural regions. PLoS Biol. 2022;20:e3001853 pubmed publisher
Gandhi P, Gawande D, Shelkar G, Gakare S, Kiritoshi T, Ji G, et al. Dysfunction of Glutamate Delta-1 Receptor-Cerebellin 1 Trans-Synaptic Signaling in the Central Amygdala in Chronic Pain. Cells. 2021;10: pubmed publisher
Haddick P, Tom I, Luis E, Quinones G, Wranik B, Ramani S, et al. Defining the ligand specificity of the deleted in colorectal cancer (DCC) receptor. PLoS ONE. 2014;9:e84823 pubmed publisher

product information

master code :

6934-CB

SKU :

6934-CB-025

product name :

Recombinant Human Cerebellin-1 Protein, CF

unit size :

25 ug

description :

The Recombinant Human Cerebellin-1 Protein, CF from R&D Systems is derived from CHO. The Recombinant Human Cerebellin-1 Protein, CF has been validated for the following applications: Bioactivity.

target :

Cerebellin-1

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

30-35 kDa (monomer) Oligomer, reducing conditions

theoretical molecular weight :

20 kDa (monomer)

gene symbol :

CBLN1

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Human Cerebellin-1 is coated at 5 ╡g/mL, biotinylated recombinant rat NRXN-1 beta binds with an apparent KD 0.5 nM. Measured by its ability to enhance neurite outgrowth of E16-E18 rat embryonic cortical neurons. Recombinant Human Cerebellin-1, immobilized at 3-30 ╡g/mL, is able to significantly enhance neurite outgrowth.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P23435

applications :

Bioactivity

source long :

Chinese Hamster Ovary cell line, CHO-derived human Cerebellin-1 protein Glu22-Leu193, with an N-terminal HA (YPYDVPDYA) tag

source short :

CHO

USD :

552 USD

alt names :

CBLN1, cerebellin 1 precursor, cerebellin-1, Cerebellin1, CLN1, Precerebellin

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage