This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Porcine IL-10 Protein
catalog :
693-PI
quantity :
10 ug
price :
339 USD
citations: 7
Reference
Williams C, Qazi U, Bernstein M, Charniak A, Gohr C, Mitton Fitzgerald E, et al. Mutations in osteoprotegerin account for the CCAL1 locus in calcium pyrophosphate deposition disease. Osteoarthritis Cartilage. 2018;26:797-806 pubmed publisher
Singleton H, Graham S, Frossard J, Bodman Smith K, Steinbach F. Infection of monocytes with European porcine reproductive and respiratory syndrome virus (PRRSV-1) strain Lena is significantly enhanced by dexamethasone and IL-10. Virology. 2018;517:199-207 pubmed publisher
Ulmasov B, Neuschwander Tetri B, Lai J, Monastyrskiy V, Bhat T, Yates M, et al. Inhibitors of Arg-Gly-Asp-Binding Integrins Reduce Development of Pancreatic Fibrosis in Mice. Cell Mol Gastroenterol Hepatol. 2016;2:499-518 pubmed publisher
Kandasamy S, Vlasova A, Fischer D, Kumar A, Chattha K, Rauf A, et al. Differential Effects of Escherichia coli Nissle and Lactobacillus rhamnosus Strain GG on Human Rotavirus Binding, Infection, and B Cell Immunity. J Immunol. 2016;196:1780-9 pubmed publisher
Sang Y, Brichalli W, Rowland R, Blecha F. Genome-wide analysis of antiviral signature genes in porcine macrophages at different activation statuses. PLoS ONE. 2014;9:e87613 pubmed publisher
Lannes N, Summerfield A. Regulation of porcine plasmacytoid dendritic cells by cytokines. PLoS ONE. 2013;8:e60893 pubmed publisher
Delputte P, Van Breedam W, Barbe F, Van Reeth K, Nauwynck H. IFN-alpha treatment enhances porcine Arterivirus infection of monocytes via upregulation of the porcine Arterivirus receptor sialoadhesin. J Interferon Cytokine Res. 2007;27:757-66 pubmed
product information
brand :
R&D Systems
master code :
693-PI
SKU :
693-PI-010
product name :
Recombinant Porcine IL-10 Protein
description :
The Recombinant Porcine IL-10 Protein from R&D Systems is derived from E. coli. The Recombinant Porcine IL-10 Protein has been validated for the following applications: Bioactivity.
target :
IL-10
category :
Proteins and Enzymes
unit size :
10 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Porcine
theoretical molecular weight :
18 kDa
gene symbol :
IL10
details of functionality :
Measured in a cell proliferation assay using MC/9-2 mouse mast cells. Thompson-Snipes, L.  et al . (1991) J. Exp. Med. 173 :507. The ED50 for this effect is 1.2-6 ng/mL.
endotoxin note :
<0.01 EU per 1 µg of the protein by the LAL method.
catalog number base :
693-PI
accessionNumbers :
Q29055
applications :
Bioactivity
source :
E. coli -derived porcine IL-10 protein Ser19-Asn175
2020 USD :
339
2021 USD :
339 USD
alt names :
CSIF, CSIFMGC126450, Cytokine synthesis inhibitory factor, GVHDS, IL10, IL10A, IL-10MGC126451, interleukin 10, interleukin-10, TGIF
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.