Recombinant Porcine IL-10 Protein | R&D Systems 693-PI-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Porcine IL-10 Protein

catalog :

693-PI-010

quantity :

10 ug

price :

423 USD

more info or order :

R&D Systems product webpage

citations: 9

Reference
Franzoni G, Anfossi A, De Ciucis C, Mecocci S, Carta T, Dei Giudici S, et al. Targeting Toll-Like Receptor 2: Polarization of Porcine Macrophages by a Mycoplasma-Derived Pam2cys Lipopeptide. Vaccines (Basel). 2021;9: pubmed publisher
Hall S, Ison S, Owles C, Coe J, Sandercock D, Zanella A. Development and validation of a multiplex fluorescent microsphere immunoassay assay for detection of porcine cytokines. MethodsX. 2019;6:1218-1227 pubmed publisher
Williams C, Qazi U, Bernstein M, Charniak A, Gohr C, Mitton Fitzgerald E, et al. Mutations in osteoprotegerin account for the CCAL1 locus in calcium pyrophosphate deposition disease. Osteoarthritis Cartilage. 2018;26:797-806 pubmed publisher
Singleton H, Graham S, Frossard J, Bodman Smith K, Steinbach F. Infection of monocytes with European porcine reproductive and respiratory syndrome virus (PRRSV-1) strain Lena is significantly enhanced by dexamethasone and IL-10. Virology. 2018;517:199-207 pubmed publisher
Ulmasov B, Neuschwander Tetri B, Lai J, Monastyrskiy V, Bhat T, Yates M, et al. Inhibitors of Arg-Gly-Asp-Binding Integrins Reduce Development of Pancreatic Fibrosis in Mice. Cell Mol Gastroenterol Hepatol. 2016;2:499-518 pubmed publisher
Kandasamy S, Vlasova A, Fischer D, Kumar A, Chattha K, Rauf A, et al. Differential Effects of Escherichia coli Nissle and Lactobacillus rhamnosus Strain GG on Human Rotavirus Binding, Infection, and B Cell Immunity. J Immunol. 2016;196:1780-9 pubmed publisher
Sang Y, Brichalli W, Rowland R, Blecha F. Genome-wide analysis of antiviral signature genes in porcine macrophages at different activation statuses. PLoS ONE. 2014;9:e87613 pubmed publisher
Lannes N, Summerfield A. Regulation of porcine plasmacytoid dendritic cells by cytokines. PLoS ONE. 2013;8:e60893 pubmed publisher
Delputte P, Van Breedam W, Barbe F, Van Reeth K, Nauwynck H. IFN-alpha treatment enhances porcine Arterivirus infection of monocytes via upregulation of the porcine Arterivirus receptor sialoadhesin. J Interferon Cytokine Res. 2007;27:757-66 pubmed

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

693-PI

SKU :

693-PI-010

product name :

Recombinant Porcine IL-10 Protein

Description :

The Recombinant Porcine IL-10 Protein from R&D Systems is derived from E. coli. The Recombinant Porcine IL-10 Protein has been validated for the following applications: Bioactivity.

target :

IL-10

category :

Proteins and Enzymes

unit size :

10 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Porcine

theoretical molecular weight :

18 kDa

gene symbol :

IL10

details of functionality :

Measured in a cell proliferation assay using MC/9-2 mouse mast cells. Thompson-Snipes, L. et al . (1991) J. Exp. Med. 173 :507. The ED50 for this effect is 1.2-6 ng/mL.

endotoxin note :

<0.01 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q29055

applications :

Bioactivity

source :

E. coli-derived Recombinant Porcine IL-10 Protein

USD :

423 USD

alt names :

CSIF, CSIFMGC126450, Cytokine synthesis inhibitory factor, GVHDS, IL10, IL10A, IL-10MGC126451, interleukin 10, interleukin-10, TGIF

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage