Recombinant P. vulgaris Chondroitinase ABC Protein, CF | R&D Systems 6877-GH-020 product information

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product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant P. vulgaris Chondroitinase ABC Protein, CF

catalog :

6877-GH-020

quantity :

20 ug

price :

373 USD

citations: 6

Reference
Volpi N, Galeotti F, Gatto F. High-throughput glycosaminoglycan extraction and UHPLC-MS/MS quantification in human biofluids. Nat Protoc. 2024;: pubmed publisher
Gutierrez Riquelme T, Karkossa I, Schubert K, Liebscher G, Packeiser E, Nolte I, et al. Proteomic analysis of extracellular vesicles derived from canine mammary tumour cell lines identifies protein signatures specific for disease state. BMC Vet Res. 2024;20:488 pubmed publisher
Blake M, Parrish D, Staffenson M, Johnson M, Woodward W, Habecker B. Loss of chondroitin sulfate proteoglycan sulfation allows delayed sympathetic reinnervation after cardiac ischemia-reperfusion. Physiol Rep. 2023;11:e15702 pubmed publisher
Queisser K, Mellema R, Middleton E, Portier I, Manne B, Denorme F, et al. COVID-19 generates hyaluronan fragments that directly induce endothelial barrier dysfunction. JCI Insight. 2021;6: pubmed publisher
Su Z, Kishida S, Tsubota S, Sakamoto K, Cao D, Kiyonari S, et al. Neurocan, an extracellular chondroitin sulfate proteoglycan, stimulates neuroblastoma cells to promote malignant phenotypes. Oncotarget. 2017;8:106296-106310 pubmed publisher
Bentzer P, Fisher J, Kong H, Mörgelin M, Boyd J, Walley K, et al. Heparin-binding protein is important for vascular leak in sepsis. Intensive Care Med Exp. 2016;4:33 pubmed

product information

master code :

6877-GH

SKU :

6877-GH-020

product name :

Recombinant P. vulgaris Chondroitinase ABC Protein, CF

unit size :

20 ug

description :

The Recombinant P. vulgaris Chondroitinase ABC Protein, CF from R&D Systems is derived from E. coli. The Recombinant P. vulgaris Chondroitinase ABC Protein, CF has been validated for the following applications: Enzyme Activity.

target :

Chondroitinase ABC

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in Tris, NaCl and Brij-35.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

P. vulgaris

observed molecular weight :

85-100 kDa, reducing conditions

theoretical molecular weight :

113 kDa

gene symbol :

NEWENTRY

details of functionality :

Measured by its ability to hydrolyze chondroitin sulfate. The specific activity is 15,000 pmol/min/╡g, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P59807

applications :

Enzyme Activity

source long :

E. coli -derived p. vulgaris Chondroitinase ABC protein Ala25-Pro1021, with an N-terminal Met and 6-His tag

source short :

E. coli

USD :

373 USD

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after opening.