Recombinant Human Dystroglycan Protein, CF | R&D Systems 6868-DG-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Dystroglycan Protein, CF

catalog :

6868-DG-050

quantity :

50 ug

price :

456 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Zhang Y, York J, Brindley M, Nunberg J, Melikyan G. Fusogenic structural changes in arenavirus glycoproteins are associated with viroporin activity. PLoS Pathog. 2023;19:e1011217 pubmed publisher
Irala D, Wang S, Sakers K, Nagendren L, Ulloa Severino F, Bindu D, et al. Astrocyte-Secreted Neurocan Controls Inhibitory Synapse Formation and Function. bioRxiv. 2023;: pubmed publisher

product information

master code :

6868-DG

SKU :

6868-DG-050

product name :

Recombinant Human Dystroglycan Protein, CF

unit size :

50 ug

description :

The Recombinant Human Dystroglycan Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Dystroglycan Protein, CF has been validated for the following applications: Bioactivity.

target :

Dystroglycan

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

65-90 kDa 20 kDa, reducing conditions

theoretical molecular weight :

67.8 kDa ( alpha subunit) 11.3 kDa (▀ subunit)

gene symbol :

DAG1

details of functionality :

Measured by the ability of the immobilized protein to enhance the adhesion of H4 human neuroglioma cells. The ED50 for this effect is 1.5-6.0 ╡g/mL. . Optimal dilutions should be determined by each laboratory for each application.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_004384

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived human Dystroglycan protein Met1-Val749, with a C-terminal 6-His tag

source short :

NS0

USD :

456 USD

alt names :

A3a, AGRNR, Dag-1, DAG1, DAG156DAG, dystroglycan, dystroglycan 1 (dystrophin-associated glycoprotein 1), Dystrophin-associated glycoprotein 1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage