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company name :
R&D Systems
product type :
protein
product name :
Recombinant Porcine IL-6 Protein, CF
catalog :
686-PI-025/CF
quantity :
25 ug
price :
447 USD
more info or order :
citations: 12
Reference
Yin S, Sun B, Xu T, Liu X, Huo L, Zhang X, et al. CHIR99021 and rpIL6 promote porcine parthenogenetic embryo development and blastocyst quality. Theriogenology. 2020;158:470-476 pubmed publisher
Hall S, Ison S, Owles C, Coe J, Sandercock D, Zanella A. Development and validation of a multiplex fluorescent microsphere immunoassay assay for detection of porcine cytokines. MethodsX. 2019;6:1218-1227 pubmed publisher
Huang T, Huang X, Chen W, Yin J, Shi B, Wang F, et al. MicroRNA responses associated with Salmonella enterica serovar typhimurium challenge in peripheral blood: effects of miR-146a and IFN-γ in regulation of fecal bacteria shedding counts in pig. BMC Vet Res. 2019;15:195 pubmed publisher
Ulmasov B, Neuschwander Tetri B, Lai J, Monastyrskiy V, Bhat T, Yates M, et al. Inhibitors of Arg-Gly-Asp-Binding Integrins Reduce Development of Pancreatic Fibrosis in Mice. Cell Mol Gastroenterol Hepatol. 2016;2:499-518 pubmed publisher
Elahi S, Thompson D, Van Kessel J, Babiuk L, Gerdts V. Protective Role of Passively Transferred Maternal Cytokines against Bordetella pertussis Infection in Newborn Piglets. Infect Immun. 2017;85: pubmed publisher
Yang S, Zhan Y, Zhou Y, Jiang Y, Zheng X, Yu L, et al. Interferon regulatory factor 3 is a key regulation factor for inducing the expression of SAMHD1 in antiviral innate immunity. Sci Rep. 2016;6:29665 pubmed publisher
Kandasamy S, Vlasova A, Fischer D, Kumar A, Chattha K, Rauf A, et al. Differential Effects of Escherichia coli Nissle and Lactobacillus rhamnosus Strain GG on Human Rotavirus Binding, Infection, and B Cell Immunity. J Immunol. 2016;196:1780-9 pubmed publisher
Delputte P, Van Breedam W, Barbe F, Van Reeth K, Nauwynck H. IFN-alpha treatment enhances porcine Arterivirus infection of monocytes via upregulation of the porcine Arterivirus receptor sialoadhesin. J Interferon Cytokine Res. 2007;27:757-66 pubmed
Saurer L, McCullough K, Summerfield A. In vitro induction of mucosa-type dendritic cells by all-trans retinoic acid. J Immunol. 2007;179:3504-14 pubmed
Kelley M, Rose A, Song K, Chen Y, Bradley J, Rookhuizen D, et al. Synergism of TNF and IL-1 in the induction of matrix metalloproteinase-3 in trabecular meshwork. Invest Ophthalmol Vis Sci. 2007;48:2634-43 pubmed
Azevedo M, Yuan L, Pouly S, Gonzales A, Jeong K, Nguyen T, et al. Cytokine responses in gnotobiotic pigs after infection with virulent or attenuated human rotavirus. J Virol. 2006;80:372-82 pubmed
Brix Christensen V, Andersen S, Andersen R, Mengel A, Dyhr T, Andersen N, et al. Acute hyperinsulinemia restrains endotoxin-induced systemic inflammatory response: an experimental study in a porcine model. Anesthesiology. 2004;100:861-70 pubmed
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
686-PI/CF
SKU :
686-PI-025/CF
product name :
Recombinant Porcine IL-6 Protein, CF
Description :
The Recombinant Porcine IL-6 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Porcine IL-6 Protein, CF has been validated for the following applications: Bioactivity.
target :
IL-6
category :
Proteins and Enzymes
unit size :
25 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Porcine
theoretical molecular weight :
21 kDa
gene symbol :
IL6
details of functionality :
Measured in a cell proliferation assay using T1165.85.2.1 mouse plasmacytoma cells. Nordan, R.P. et al . (1987) J. Immunol. 139 :813. The ED50 for this effect is typically 0.3-1.8 ng/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P26893
applications :
Bioactivity
source :
E. coli-derived Recombinant Porcine IL-6 Protein
USD :
447 USD
alt names :
B-cell differentiation factor, B-cell stimulatory factor 2, BSF2, BSF-2, CDF, CTL differentiation factor, HSF, hybridoma growth factor, IFNB2, IFN-beta-2, IL6, IL-6, Interferon beta-2, interleukin 6 (interferon, beta 2), interleukin BSF-2, interleukin-6, MGI-2A
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.