Recombinant Human FGFR2 beta (IIIc) Fc Chimera Protein, CF | R&D Systems 684-FR-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human FGFR2 beta (IIIc) Fc Chimera Protein, CF

catalog :

684-FR-050

quantity :

50 ug

price :

431 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Yashiro M, Kuroda K, Masuda G, Okuno T, Miki Y, Yamamoto Y, et al. Clinical difference between fibroblast growth factor receptor 2 subclass, type IIIb and type IIIc, in gastric cancer. Sci Rep. 2021;11:4698 pubmed publisher
Lan Y, Li X, Liu Y, He Y, Hao C, Wang H, et al. Pingyangmycin inhibits glycosaminoglycan sulphation in both cancer cells and tumour tissues. J Cell Mol Med. 2020;24:3419-3430 pubmed publisher
Chan W, Howe K, Clegg J, Guimond S, Price D, Turnbull J, et al. 2-O Heparan Sulfate Sulfation by Hs2st Is Required for Erk/Mapk Signalling Activation at the Mid-Gestational Mouse Telencephalic Midline. PLoS ONE. 2015;10:e0130147 pubmed publisher
Jaskoll T, Witcher D, Toreno L, Bringas P, Moon A, Melnick M. FGF8 dose-dependent regulation of embryonic submandibular salivary gland morphogenesis. Dev Biol. 2004;268:457-69 pubmed

product information

master code :

684-FR

SKU :

684-FR-050

product name :

Recombinant Human FGFR2 beta (IIIc) Fc Chimera Protein, CF

unit size :

50 ug

description :

The Recombinant Human FGFR2 beta (IIIc) Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human FGFR2 beta (IIIc) Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

FGFR2 beta

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

100 kDa, reducing conditions

theoretical molecular weight :

56 kDa (monomer)

gene symbol :

FGFR2

details of functionality :

Measured by its ability to inhibit FGF acidic-dependent proliferation of NR6R-3T3 mouse fibroblast cells. The ED50 for this effect is 1-3áng/mL.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_001138387

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived human FGF R2 beta protein Human FGF R2▀ (IIIc) (Arg22 - Glu288) (Leu27 - Glu288) Accession # NP_001138387 IEGRMD Human IgG1 (Pro100 - Lys330) N-terminus C-terminus

source short :

NS0

USD :

431 USD

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage