Recombinant Human IL-36 beta/IL-1F8 (aa 5-157) Protein | R&D Systems 6834-ILB product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human IL-36 beta/IL-1F8 (aa 5-157) Protein

catalog :

6834-ILB

quantity :

25 ug

price :

339 USD

citations: 3

Reference
Swindell W, Beamer M, Sarkar M, Loftus S, Fullmer J, Xing X, et al. RNA-Seq Analysis of IL-1B and IL-36 Responses in Epidermal Keratinocytes Identifies a Shared MyD88-Dependent Gene Signature. Front Immunol. 2018;9:80 pubmed publisher
Yi G, Ybe J, Saha S, Caviness G, Raymond E, Ganesan R, et al. Structural and Functional Attributes of the Interleukin-36 Receptor. J Biol Chem. 2016;291:16597-609 pubmed publisher
Saha S, Singh D, Raymond E, Ganesan R, Caviness G, Grimaldi C, et al. Signal Transduction and Intracellular Trafficking by the Interleukin 36 Receptor. J Biol Chem. 2015;290:23997-4006 pubmed publisher

product information

brand :

R&D Systems

master code :

6834-ILB

SKU :

6834-ILB-025

product name :

Recombinant Human IL-36 beta/IL-1F8 (aa 5-157) Protein

description :

The Recombinant Human IL-36 beta/IL-1F8 (aa 5-157) Protein from R&D Systems is derived from E. coli. The Recombinant Human IL-36 beta/IL-1F8 (aa 5-157) Protein has been validated for the following applications: Bioactivity.

target :

IL-36 beta / IL-1F8

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

main entrez gene id :

27177

purity :

>95%, by SDS-PAGE with silver staining.

species :

Human

observed molecular weight :

17 kDa, reducing conditions

theoretical molecular weight :

17 kDa

gene symbol :

IL36B

details of functionality :

Measured by its ability to induce IL-8 secretion in A431 human epithelial carcinoma cells. The ED50 for this effect is 0.8-4.8 ng/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

catalog number base :

6834-ILB

accessionNumbers :

NP_775270

applications :

Bioactivity

source :

The Recombinant Human IL-36 beta / IL-1F8 (aa 5-157) Protein from R&D Systems is derived from E. coli. The Recombinant Human IL-36 beta / IL-1F8 (aa 5-157) Protein has been validated for the following applications: Bioactivity.

USD :

339 USD

alt names :

family of interleukin 1-eta, FIL1, FIL1 eta, FIL1-(ETA), FIL1H, FILI-(ETA), IL-1 eta, IL1-ETA, IL1F8, IL-1F8, IL1F8 (Canonical product IL-1F8a), IL-1F8 (FIL1-eta), IL1H2, IL-1H2, IL36 beta, IL36B, interleukin 1 family, member 8 (eta), interleukin 1, eta, Interleukin 36, Beta, Interleukin-1 eta, interleukin-1 family member 8, Interleukin-1 homolog 2, Interleukin-1 Superfamily e, Interleukin-36 Beta

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.