product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human IL-36 beta/IL-1F8 (aa 5-157) Protein
catalog :
6834-ILB-025
quantity :
25 ug
price :
400 USD
more info or order :
R&D Systems product webpage
citations: 3
Reference
Swindell W, Beamer M, Sarkar M, Loftus S, Fullmer J, Xing X, et al. RNA-Seq Analysis of IL-1B and IL-36 Responses in Epidermal Keratinocytes Identifies a Shared MyD88-Dependent Gene Signature. Front Immunol. 2018;9:80 pubmed publisher
Yi G, Ybe J, Saha S, Caviness G, Raymond E, Ganesan R, et al. Structural and Functional Attributes of the Interleukin-36 Receptor. J Biol Chem. 2016;291:16597-609 pubmed publisher
Saha S, Singh D, Raymond E, Ganesan R, Caviness G, Grimaldi C, et al. Signal Transduction and Intracellular Trafficking by the Interleukin 36 Receptor. J Biol Chem. 2015;290:23997-4006 pubmed publisher
product information
master code :
6834-ILB
SKU :
6834-ILB-025
product name :
Recombinant Human IL-36 beta/IL-1F8 (aa 5-157) Protein
unit size :
25 ug
description :
The Recombinant Human IL-36 beta/IL-1F8 (aa 5-157) Protein from R&D Systems is derived from E. coli. The Recombinant Human IL-36 beta/IL-1F8 (aa 5-157) Protein has been validated for the following applications: Bioactivity.
target :
IL-36 beta/IL-1F8
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE with silver staining.
species :
Human
observed molecular weight :
17 kDa, reducing conditions
theoretical molecular weight :
17 kDa
gene symbol :
IL36B
details of functionality :
Measured by its ability to induce IL-8 secretion in A431 human epithelial carcinoma cells. The ED50 for this effect is 0.8-4.8 ng/mL.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
top caption :
Recombinant Human IL-36 beta/IL-1F8 (aa 5-157) Protein Bioactivity
accessionNumbers :
NP_775270
applications :
Bioactivity
source long :
E. coli -derived human IL-36 beta/IL-1F8 protein Arg5-Glu157
source short :
E. coli
USD :
400 USD
alt names :
family of interleukin 1-eta, FIL1, FIL1 eta, FIL1-(ETA), FIL1H, FILI-(ETA), IL-1 eta, IL1-ETA, IL1F8, IL-1F8, IL1F8 (Canonical product IL-1F8a), IL-1F8 (FIL1-eta), IL1H2, IL-1H2, IL36 beta, IL36B, interleukin 1 family, member 8 (eta), interleukin 1, eta, Interleukin 36, Beta, Interleukin-1 eta, interleukin-1 family member 8, Interleukin-1 homolog 2, Interleukin-1 Superfamily e, Interleukin-36 Beta
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.