Recombinant Human EphA8 Fc Chimera Protein, CF | R&D Systems 6828-A8-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human EphA8 Fc Chimera Protein, CF

catalog :

6828-A8-050

quantity :

50 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 1

Reference
Cha J, Chan L, Wang Y, Chu Y, Wang C, Lee H, et al. Ephrin receptor A10 monoclonal antibodies and the derived chimeric antigen receptor T cells exert an antitumor response in mouse models of triple-negative breast cancer. J Biol Chem. 2022;298:101817 pubmed publisher

product information

master code :

6828-A8

SKU :

6828-A8-050

product name :

Recombinant Human EphA8 Fc Chimera Protein, CF

unit size :

50 ug

description :

The Recombinant Human EphA8 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human EphA8 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

EphA8

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in MES, NaCl, PEG, CHAPS and Imidazole.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

94 kDa, reducing conditions

theoretical molecular weight :

83.2 kDa (monomer)

gene symbol :

EPHA8

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Human EphA8 Fc Chimera is coated at 2 ╡g/mL (100 ╡L/well), the concentration of Biotinylayed Recombinant Human Ephrin-A5 Fc Chimera (Catalog # BT374 ) that produces 50% of the optimal binding response is 2-12 ng/mL.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_065387

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived human EphA8 protein Human EphA8 (Glu31-Thr542) Accession # NP_065387 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus

source short :

NS0

USD :

432 USD

alt names :

EEK, EK3, EPH- and ELK-related kinase, EPH- and ELK-related tyrosine kinase, EPH receptor A8, EPH-like kinase 3, ephrin type-A receptor 8, HEK3, hydroxyaryl-protein kinase, KIAA1459, protein-tyrosine kinase, tyrosine-protein kinase receptor EEK, tyrosylprotein kinase

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after opening. 3 months, -20 to -70 ░C under sterile conditions after opening.

more info or order :

R&D Systems product webpage