Recombinant Human EphA4 Fc Chimera Protein, CF | R&D Systems 6827-A4-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human EphA4 Fc Chimera Protein, CF

catalog :

6827-A4-050

quantity :

50 ug

price :

443 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Cha J, Chan L, Wang Y, Chu Y, Wang C, Lee H, et al. Ephrin receptor A10 monoclonal antibodies and the derived chimeric antigen receptor T cells exert an antitumor response in mouse models of triple-negative breast cancer. J Biol Chem. 2022;298:101817 pubmed publisher
Teo L, Boghdadi A, Homman Ludiye J, Mundiñano I, Kwan W, Bourne J. Replicating infant-specific reactive astrocyte functions in the injured adult brain. Prog Neurobiol. 2021;204:102108 pubmed publisher
Schoonaert L, Rue L, Roucourt B, Timmers M, Little S, Chávez Gutiérrez L, et al. Identification and characterization of Nanobodies targeting the EphA4 receptor. J Biol Chem. 2017;292:11452-11465 pubmed publisher

product information

master code :

6827-A4

SKU :

6827-A4-050

product name :

Recombinant Human EphA4 Fc Chimera Protein, CF

unit size :

50 ug

description :

The Recombinant Human EphA4 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human EphA4 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

EphA4

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

93-98 kDa, reducing conditions

theoretical molecular weight :

85 kDa (monomer)

gene symbol :

EPHA4

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Human EphA4 Fc Chimera is coated at 2 ╡g/mL (100 ╡L/well), the concentration of biotinylayed Recombinant Human Ephrin-A5 Fc Chimera (Catalog # 374-EA) that produces 50% of the optimal binding response is found to be approximately 5-25 ng/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_004429.1

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived human EphA4 protein Human EphA4 (Met1 - Thr547) Accession # NP_004429.1 IEGRMD Human IgG1 (Pro100 - Lys330) N-terminus C-terminus

source short :

NS0

USD :

443 USD

alt names :

Cek8, EC 2.7.10, EC 2.7.10.1, EK8, EPH receptor A4, EphA4, EPH-like kinase 8, ephrin type-A receptor 4, HEK8, receptor protein-tyrosine kinase HEK8, SEK, Sek1, Tyro1, TYRO1 protein tyrosine kinase, Tyrosine-protein kinase receptor SEK, Tyrosine-protein kinase TYRO1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage