Recombinant Mouse Cadherin-6/KCAD Protein, CF | R&D Systems 6826-CA-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse Cadherin-6/KCAD Protein, CF

catalog :

6826-CA-050

quantity :

50 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 1

Reference
Suzuki H, Nagase S, Saito C, Takatsuka A, Nagata M, Honda K, et al. Raludotatug Deruxtecan, a CDH6-Targeting Antibody-Drug Conjugate with a DNA Topoisomerase I Inhibitor DXd, Is Efficacious in Human Ovarian and Kidney Cancer Models. Mol Cancer Ther. 2024;23:257-271 pubmed publisher

product information

master code :

6826-CA

SKU :

6826-CA-050

product name :

Recombinant Mouse Cadherin-6/KCAD Protein, CF

unit size :

50 ug

description :

The Recombinant Mouse Cadherin-6/KCAD Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse Cadherin-6/KCAD Protein, CF has been validated for the following applications: Bioactivity.

target :

Cadherin-6/KCAD

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

observed molecular weight :

90-105 kDa, reducing conditions

theoretical molecular weight :

67.0 kDa (pro-protein) 63.3 kDa (mature protein)

details of functionality :

Measured by the ability of the immobilized protein to support the adhesion of Caki-2 human clear cell carcinoma epithelial cells. The ED50 for this effect is 0.2-1.0 ╡g/mL after a 30 minutes incubation at 37 ░C. Optimal dilutions should be determined by each laboratory for each application.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_031692

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived mouse Cadherin-6/KCAD protein Met1-Ala615 with a C-terminal 6-His tag

source short :

NS0

USD :

432 USD

alt names :

cadherin 6, type 2, K-cadherin (fetal kidney), cadherin, fetal kidney, cadherin-6, Cadherin6, CDH6, KCAD, K-Cadherin, K-cadherin (fetal kidney)

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage