Recombinant Human Prolactin Protein, CF | R&D Systems 682-PL-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Prolactin Protein, CF

catalog :

682-PL-050

quantity :

50 ug

price :

349 USD

more info or order :

R&D Systems product webpage

citations: 7

Reference
Chattopadhyay M, Jenkins E, Janssen W, Mashaka T, Germain D. Idiosyncratic nature of lactation reveals link to breast cancer risk. Res Sq. 2024;: pubmed publisher
Munne P, Martikainen L, Räty I, Bertula K, Nonappa -, Ruuska J, et al. Compressive stress-mediated p38 activation required for ERα + phenotype in breast cancer. Nat Commun. 2021;12:6967 pubmed publisher
Anders P, Song X, György B, Szentmary N, Seitz B, Gatzioufas Z. Effect of prolactin on normal and keratoconus human corneal stromal fibroblasts in vitro. PLoS ONE. 2021;16:e0249344 pubmed publisher
Han L, Zhang M, Xing Z, Coleman D, Liang Y, Loor J, et al. Knockout of butyrophilin subfamily 1 member A1 (BTN1A1) alters lipid droplet formation and phospholipid composition in bovine mammary epithelial cells. J Anim Sci Biotechnol. 2020;11:72 pubmed publisher
Oliveira Ferrer L, Wellbrock J, Bartsch U, Penas E, Hauschild J, Klokow M, et al. Combination therapy targeting integrins reduces glioblastoma tumor growth through antiangiogenic and direct antitumor activity and leads to activation of the pro-proliferative prolactin pathway. Mol Cancer. 2013;12:144 pubmed publisher
Xu D, Lin L, Lin X, Huang Z, Lei Z. Immunoregulation of autocrine prolactin: suppressing the expression of costimulatory molecules and cytokines in T lymphocytes by prolactin receptor knockdown. Cell Immunol. 2010;263:71-8 pubmed publisher
Chakravarti P, Henry M, Quelle F. Prolactin and heregulin override DNA damage-induced growth arrest and promote phosphatidylinositol-3 kinase-dependent proliferation in breast cancer cells. Int J Oncol. 2005;26:509-14 pubmed

product information

master code :

682-PL

SKU :

682-PL-050

product name :

Recombinant Human Prolactin Protein, CF

unit size :

50 ug

description :

The Recombinant Human Prolactin Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human Prolactin Protein, CF has been validated for the following applications: Bioactivity.

target :

Prolactin

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Phosphate and NaCl.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

theoretical molecular weight :

24 kDa

gene symbol :

PRL

details of functionality :

Measured in a cell proliferation assay using Nb2-11 rat lymphoma cells. Gout, P.W. et al . (1980) Cancer Res. 40 :2433. The ED50 for this effect is 0.03-0.1áng/mL.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q5THQ0

applications :

Bioactivity

source long :

E. coli -derived human Prolactin protein Leu29-Cys227, with an N-terminal Met

source short :

E. coli

USD :

349 USD

alt names :

PRL, prolactin

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage