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company name :
R&D Systems
product type :
protein
product name :
Recombinant Porcine IL-1 beta/IL-1F2 Protein, CF
catalog :
681-PI-010/CF
quantity :
10 ug
price :
373 USD
more info or order :
citations: 11
Reference
Dresen M, Schenk J, Berhanu Weldearegay Y, Vötsch D, Baumgartner W, Valentin Weigand P, et al. Streptococcus suis Induces Expression of Cyclooxygenase-2 in Porcine Lung Tissue. Microorganisms. 2021;9: pubmed publisher
Cho H, Bhatti F, Hasty K, Yi A. Nanosome-Mediated Delivery Of Protein Kinase D Inhibitor Protects Chondrocytes From Interleukin-1β-Induced Stress And Apoptotic Death. Int J Nanomedicine. 2019;14:8835-8846 pubmed publisher
Hall S, Ison S, Owles C, Coe J, Sandercock D, Zanella A. Development and validation of a multiplex fluorescent microsphere immunoassay assay for detection of porcine cytokines. MethodsX. 2019;6:1218-1227 pubmed publisher
Tabeian H, Betti B, Dos Santos Cirqueira C, de Vries T, Lobbezoo F, Ter Linde A, et al. IL-1β Damages Fibrocartilage and Upregulates MMP-13 Expression in Fibrochondrocytes in the Condyle of the Temporomandibular Joint. Int J Mol Sci. 2019;20: pubmed publisher
Park H, Liu G, Liu Q, Zhou Y. Swine Influenza Virus Induces RIPK1/DRP1-Mediated Interleukin-1 Beta Production. Viruses. 2018;10: pubmed publisher
Park H, Liu G, Thulasi Raman S, Landreth S, Liu Q, Zhou Y. NS1 Protein of 2009 Pandemic Influenza A Virus Inhibits Porcine NLRP3 Inflammasome-Mediated Interleukin-1 Beta Production by Suppressing ASC Ubiquitination. J Virol. 2018;92: pubmed publisher
Comblain F, Sanchez C, Lesponne I, Balligand M, Serisier S, Henrotin Y. Curcuminoids extract, hydrolyzed collagen and green tea extract synergically inhibit inflammatory and catabolic mediator's synthesis by normal bovine and osteoarthritic human chondrocytes in monolayer. PLoS ONE. 2015;10:e0121654 pubmed publisher
Delputte P, Van Breedam W, Barbe F, Van Reeth K, Nauwynck H. IFN-alpha treatment enhances porcine Arterivirus infection of monocytes via upregulation of the porcine Arterivirus receptor sialoadhesin. J Interferon Cytokine Res. 2007;27:757-66 pubmed
Kelley M, Rose A, Song K, Chen Y, Bradley J, Rookhuizen D, et al. Synergism of TNF and IL-1 in the induction of matrix metalloproteinase-3 in trabecular meshwork. Invest Ophthalmol Vis Sci. 2007;48:2634-43 pubmed
Johannisson A, Jonasson R, Dernfalk J, Jensen Waern M. Simultaneous detection of porcine proinflammatory cytokines using multiplex flow cytometry by the xMAP technology. Cytometry A. 2006;69:391-5 pubmed
Wheaton A, Dodge G, Borthakur A, Kneeland J, Schumacher H, Reddy R. Detection of changes in articular cartilage proteoglycan by T(1rho) magnetic resonance imaging. J Orthop Res. 2005;23:102-8 pubmed
product information
master code :
681-PI/CF
SKU :
681-PI-010/CF
product name :
Recombinant Porcine IL-1 beta/IL-1F2 Protein, CF
unit size :
10 ug
description :
The Recombinant Porcine IL-1 beta/IL-1F2 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Porcine IL-1 beta/IL-1F2 Protein, CF has been validated for the following applications: Bioactivity.
target :
IL-1 beta/IL-1F2
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Porcine
theoretical molecular weight :
18 kDa
gene symbol :
IL1B1
details of functionality :
Measured in a cell proliferation assay using D10.G4.1 mouse helper T cells. Symons, J.A. etáal . (1987) in Lymphokines and Interferons, a Practical Approach. Clemens, M.J. etáal . (eds): IRL Press. 272. The ED50 for this effect is 0.75-4.5 ng/mL.
endotoxin note :
<1.0 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
P26889.1
applications :
Bioactivity
source long :
E. coli -derived porcine IL-1 beta/IL-1F2 protein Ala115-Pro267
source short :
E. coli
USD :
373 USD
alt names :
catabolin, IL-1, IL1 beta, IL-1 beta, IL-1b, IL1B, IL1-BETA, IL-1F2, IL1F2IL-1 beta, interleukin 1, beta, interleukin-1 beta, preinterleukin 1 beta, pro-interleukin-1-beta
storage :
12 months from date of receipt, <= -20 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, <= -20 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.