Recombinant Porcine IL-1 alpha/IL-1F1 Protein | R&D Systems 680-PI-010 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Porcine IL-1 alpha/IL-1F1 Protein

catalog :

680-PI-010

quantity :

10 ug

price :

373 USD

citations: 6

Reference
Libke M, Cunningham D, Furman B, Yi J, Brunger J, Kraus V, et al. Mode of injury and level of synovitis alter inflammatory chondrocyte gene expression and associated pathways. Sci Rep. 2024;14:28917 pubmed publisher
Rosas S, Kwok A, Moore J, Shi L, Smith T, Tallant E, et al. Osteoarthritis as a Systemic Disease Promoted Prostate Cancer In Vivo and In Vitro. Int J Mol Sci. 2024;25: pubmed publisher
Delputte P, Van Breedam W, Barbe F, Van Reeth K, Nauwynck H. IFN-alpha treatment enhances porcine Arterivirus infection of monocytes via upregulation of the porcine Arterivirus receptor sialoadhesin. J Interferon Cytokine Res. 2007;27:757-66 pubmed
McNulty A, Moutos F, Weinberg J, Guilak F. Enhanced integrative repair of the porcine meniscus in vitro by inhibition of interleukin-1 or tumor necrosis factor alpha. Arthritis Rheum. 2007;56:3033-42 pubmed
Kelley M, Rose A, Song K, Chen Y, Bradley J, Rookhuizen D, et al. Synergism of TNF and IL-1 in the induction of matrix metalloproteinase-3 in trabecular meshwork. Invest Ophthalmol Vis Sci. 2007;48:2634-43 pubmed
Pritchard S, Guilak F. Effects of interleukin-1 on calcium signaling and the increase of filamentous actin in isolated and in situ articular chondrocytes. Arthritis Rheum. 2006;54:2164-74 pubmed

product information

master code :

680-PI

SKU :

680-PI-010

product name :

Recombinant Porcine IL-1 alpha/IL-1F1 Protein

unit size :

10 ug

description :

The Recombinant Porcine IL-1 alpha/IL-1F1 Protein from R&D Systems is derived from E. coli. The Recombinant Porcine IL-1 alpha/IL-1F1 Protein has been validated for the following applications: Bioactivity.

target :

IL-1 alpha/IL-1F1

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS and DTT with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Porcine

theoretical molecular weight :

17.5 kDa

gene symbol :

IL1A

details of functionality :

Measured in a cell proliferation assay using D10.G4.1 mouse helper T cells. Symons, J.A. etáal . (1987) in Lymphokines and Interferons, a Practical Approach. Clemens, M.J. etáal . (eds): IRL Press. 272. The ED50 for this effect is 10-60 pg/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P18430

applications :

Bioactivity

source long :

E. coli -derived porcine IL-1 alpha/IL-1F1 protein Gln119-Ser270, with an N-terminal Met

source short :

E. coli

USD :

373 USD

alt names :

BAF, Hematopoietin-1, IL1, IL1 alpha, IL-1 alpha, IL1A, IL-1A, IL1-ALPHA, IL1F1, IL-1F1, IL1F1hematopoietin-1, interleukin 1, alpha, interleukin-1 alpha, LAF, LEM, preinterleukin 1 alpha, pro-interleukin-1-alpha

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.