product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Lymphotoxin alpha2/beta1 Protein
catalog :
679-TX-010
quantity :
10 ug
price :
417 USD
more info or order :
R&D Systems product webpage
citations: 3
Reference
Clarke A, Poulton L, Shim D, Mabon D, Butt D, Pollard M, et al. An anti-TL1A antibody for the treatment of asthma and inflammatory bowel disease. MAbs. 2018;10:664-677 pubmed publisher
Kitamura J, Uemura M, Kurozumi M, Sonobe M, Manabe T, Hiai H, et al. Chronic lung injury by constitutive expression of activation-induced cytidine deaminase leads to focal mucous cell metaplasia and cancer. PLoS ONE. 2015;10:e0117986 pubmed publisher
Matsui H, Hikichi Y, Tsuji I, Yamada T, Shintani Y. LIGHT, a member of the tumor necrosis factor ligand superfamily, prevents tumor necrosis factor-alpha-mediated human primary hepatocyte apoptosis, but not Fas-mediated apoptosis. J Biol Chem. 2002;277:50054-61 pubmed
product information
brand :
R&D Systems
master code :
679-TX
SKU :
679-TX-010
product name :
Recombinant Human Lymphotoxin alpha2/beta1 Protein
description :
The Recombinant Human Lymphotoxin alpha2/beta1 Protein from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Human Lymphotoxin alpha2/beta1 Protein has been validated for the following applications: Bioactivity.
target :
Lymphotoxin
category :
Proteins and Enzymes
unit sizes :
10 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
observed molecular weight :
18-26 kDa, reducing conditions
theoretical molecular weight :
18 kDa (LT alpha ), 18.5 kDa ( LT beta )
gene symbol :
LTA
details of functionality :
Measured in a cytotoxicity assay using L-929 mouse fibroblast cells. The ED50 for this effect is 0.5-3 ng/mL.
endotoxin note :
<1.0 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P01374 (LT alpha ) Q06643 (LT beta )
applications :
Bioactivity
source :
Sf 21 (baculovirus)-derived Recombinant Human Lymphotoxin alpha2/beta1 Protein
USD :
417 USD
alt names :
LT, Lymphotoxin alpha, tnfb, TNFSF1, TNLG1E
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.