Recombinant Human Lymphotoxin alpha2/beta1 Protein | R&D Systems 679-TX-010 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Lymphotoxin alpha2/beta1 Protein

catalog :

679-TX-010

quantity :

10 ug

price :

456 USD

citations: 3

Reference
Clarke A, Poulton L, Shim D, Mabon D, Butt D, Pollard M, et al. An anti-TL1A antibody for the treatment of asthma and inflammatory bowel disease. MAbs. 2018;10:664-677 pubmed publisher
Kitamura J, Uemura M, Kurozumi M, Sonobe M, Manabe T, Hiai H, et al. Chronic lung injury by constitutive expression of activation-induced cytidine deaminase leads to focal mucous cell metaplasia and cancer. PLoS ONE. 2015;10:e0117986 pubmed publisher
Matsui H, Hikichi Y, Tsuji I, Yamada T, Shintani Y. LIGHT, a member of the tumor necrosis factor ligand superfamily, prevents tumor necrosis factor-alpha-mediated human primary hepatocyte apoptosis, but not Fas-mediated apoptosis. J Biol Chem. 2002;277:50054-61 pubmed

product information

master code :

679-TX

SKU :

679-TX-010

product name :

Recombinant Human Lymphotoxin alpha2/beta1 Protein

unit size :

10 ug

description :

The Recombinant Human Lymphotoxin alpha2/beta1 Protein from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Human Lymphotoxin alpha2/beta1 Protein has been validated for the following applications: Bioactivity.

target :

Lymphotoxin

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

18-26 kDa, reducing conditions

theoretical molecular weight :

18 kDa (LT alpha ), 18.5 kDa ( LT▀)

gene symbol :

LTA

details of functionality :

Measured in a cytotoxicity assay using L-929 mouse fibroblast cells. The ED50 for this effect is 0.5-3 ng/mL.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P01374 (LT alpha ) Q06643 (LT▀)

applications :

Bioactivity

source long :

Spodoptera frugiperda , Sf 21 (baculovirus)-derived human Lymphotoxin protein Leu35-Leu205 (LT alpha ) & Leu54-Gly244 (LT▀), both with an N-terminal Met & Thr41 - Leu205 (LT alpha )

source short :

Sf 21 (baculovirus)

USD :

456 USD

alt names :

LT, Lymphotoxin alpha, tnfb, TNFSF1, TNLG1E

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.