product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse FCRN Protein, CF
catalog :
6775-FC-050
quantity :
50 ug
price :
417 USD
more info or order :
R&D Systems product webpage
citations: 2
Reference
Leoh L, Kim Y, Candelaria P, Martinez Maza O, Daniels Wells T, Penichet M. Efficacy and Mechanism of Antitumor Activity of an Antibody Targeting Transferrin Receptor 1 in Mouse Models of Human Multiple Myeloma. J Immunol. 2018;200:3485-3494 pubmed publisher
Ingram J, Tursi S, Zhang T, Guo W, Yin C, A Wynosky Dolfi M, et al. A Nonpyroptotic IFN-γ-Triggered Cell Death Mechanism in Nonphagocytic Cells Promotes Salmonella Clearance In Vivo. J Immunol. 2018;200:3626-3634 pubmed publisher
product information
brand :
R&D Systems
master code :
6775-FC
SKU :
6775-FC-050
product name :
Recombinant Mouse FCRN Protein, CF
description :
The Recombinant Mouse FCRN Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse FCRN Protein, CF has been validated for the following applications: Bioactivity.
target :
FCRN
category :
Proteins and Enzymes
unit sizes :
50 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS, NaCl and Triton
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Mouse
observed molecular weight :
45-47 kDa, reducing conditions
theoretical molecular weight :
32.3 kDa
gene symbol :
Fcgrt
details of functionality :
Measured by its binding ability in a functional ELISA. When Recombinant Mouse FCRN is immobilized at 0.5 µg/mL (100 µL/well), the concentration of human IgG that produces 50% of the optimal binding response is found to be approximately 2-10 µg/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
AAH03786
applications :
Bioactivity
source :
NS0-derived Recombinant Mouse FCRN Protein, CF
USD :
417 USD
alt names :
alpha-chain, Fc fragment of IgG, receptor, transporter, alpha, FCGRT, FcRn, FcRn alpha chain, FCRNimmunoglobulin receptor, intestinal, heavy chain, IgG Fc fragment receptor transporter alpha chain, IgG receptor FcRn large subunit p51, major histocompatibility complex class I-like Fc receptor, Neonatal Fc receptor, neonatal Fc-receptor for Ig
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.