product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Cadherin-7 (CAD-7) Protein, CF
catalog :
6774-CA-050
quantity :
50 ug
price :
524 USD
more info or order :
R&D Systems product webpage
citations: 1
Reference
Suzuki H, Nagase S, Saito C, Takatsuka A, Nagata M, Honda K, et al. Raludotatug Deruxtecan, a CDH6-Targeting Antibody-Drug Conjugate with a DNA Topoisomerase I Inhibitor DXd, Is Efficacious in Human Ovarian and Kidney Cancer Models. Mol Cancer Ther. 2024;23:257-271 pubmed publisher
product information
master code :
6774-CA
SKU :
6774-CA-050
product name :
Recombinant Human Cadherin-7 (CAD-7) Protein, CF
unit size :
50 ug
description :
The Recombinant Human Cadherin-7 (CAD-7) Protein, CF from R&D Systems is derived from CHO. The Recombinant Human Cadherin-7 (CAD-7) Protein, CF has been validated for the following applications: Bioactivity.
target :
Cadherin-7
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
observed molecular weight :
80 - 90 kDa, reducing conditions
theoretical molecular weight :
62.2 kDa
gene symbol :
CDH7
details of functionality :
Measured by the ability of the immobilized protein to support the adhesion of U-87 MG human glioblastoma/astrocytoma cells. The ED50 for this effect is 1.0-4.0 ╡g/mL. . Optimal dilutions should be determined by each laboratory for each application.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
BAA87415
applications :
Bioactivity
source long :
Chinese Hamster Ovary cell line, CHO-derived human Cadherin-7 protein Met1-Thr607, with a C-terminal 6-His tag
source short :
CHO
USD :
524 USD
alt names :
CAD7, cadherin 7, type 2, cadherin-7, Cadherin7, CDH7, CDH7L1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.