Recombinant Human IL-32 beta Protein, CF | R&D Systems 6769-IL-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human IL-32 beta Protein, CF

catalog :

6769-IL-025

quantity :

25 ug

price :

423 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Gong L, Liu G, Zhu H, Li C, Li P, Liu C, et al. IL-32 induces epithelial-mesenchymal transition by triggering endoplasmic reticulum stress in A549 cells. BMC Pulm Med. 2020;20:278 pubmed publisher
Gorvel L, Korenfeld D, Tung T, Klechevsky E. Dendritic Cell-Derived IL-32?: A Novel Inhibitory Cytokine of NK Cell Function. J Immunol. 2017;199:1290-1300 pubmed publisher
Osman A, Bhuyan F, Hashimoto M, Nasser H, Maekawa T, Suzu S. M-CSF inhibits anti-HIV-1 activity of IL-32, but they enhance M2-like phenotypes of macrophages. J Immunol. 2014;192:5083-9 pubmed publisher
Sakitani K, Hirata Y, Hayakawa Y, Serizawa T, Nakata W, Takahashi R, et al. Role of interleukin-32 in Helicobacter pylori-induced gastric inflammation. Infect Immun. 2012;80:3795-803 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

6769-IL

SKU :

6769-IL-025

product name :

Recombinant Human IL-32 beta Protein, CF

Description :

The Recombinant Human IL-32 beta Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human IL-32 beta Protein, CF has been validated for the following applications: Bioactivity.

target :

IL-32 beta

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

Supplied as a 0.2 µm filtered solution in HEPES, NaCl, DTT and CHAPS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

theoretical molecular weight :

23.1 kDa

details of functionality :

Measured by its ability to induce TNF-alpha secretion by RAW 264.7 mouse monocyte/macrophage cells under serum free conditions in the presence of 10 µg/mL of Polymyxin B. Kim, S.H. et al . (2005) Immunity 22 :131. The ED50 for this effect is 10-50 ng/mL.

endotoxin note :

<1.0 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

NP_001012649

applications :

Bioactivity

source :

E. coli-derived Recombinant Human IL-32 beta Protein

USD :

423 USD

alt names :

IL32, IL32 beta, IL-32alpha, IL-32beta, IL-32delta, IL-32gamma, interleukin 32, NK4, TAIF, TAIFa, TAIFb, TAIFc, TAIFd

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after opening. 3 months, -20 to -70 °C under sterile conditions after opening.

more info or order :

R&D Systems product webpage