Recombinant Human PDGF R alpha Fc Chimera Protein, CF | R&D Systems 6765-PR product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human PDGF R alpha Fc Chimera Protein, CF

catalog :

6765-PR

quantity :

50 ug

price :

369 USD

citations: 2

Reference
Stegmann C, Hochdorfer D, Lieber D, Subramanian N, Stöhr D, Laib Sampaio K, et al. A derivative of platelet-derived growth factor receptor alpha binds to the trimer of human cytomegalovirus and inhibits entry into fibroblasts and endothelial cells. PLoS Pathog. 2017;13:e1006273 pubmed publisher
Wu Y, Prager A, Boos S, Resch M, Brizic I, Mach M, et al. Human cytomegalovirus glycoprotein complex gH/gL/gO uses PDGFR-α as a key for entry. PLoS Pathog. 2017;13:e1006281 pubmed publisher

product information

brand :

R&D Systems

master code :

6765-PR

SKU :

6765-PR-050

product name :

Recombinant Human PDGF R alpha Fc Chimera Protein, CF

description :

The Recombinant Human PDGF R alpha Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human PDGF R alpha Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

PDGFR alpha

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

110-130 kDa, reducing conditions

theoretical molecular weight :

82.8 kDa (monomer)

gene symbol :

PDGFRA

details of functionality :

Measured by its ability to inhibit the biological activity of PDGF-AB or PDGF-AA using NR6R-3T3 mouse fibroblast cells. Raines, E.W. et al . (1985) Methods Enzymol. 109 :749. The ED50 for this effect is 0.2-1 µg/mL in the presence of 100 ng/mL recombinant human PDGF-AB.

endotoxin note :

<0.01 EU per 1 µg of the protein by the LAL method.

catalog number base :

6765-PR

accessionNumbers :

P16234

applications :

Bioactivity

source :

Mouse myeloma cell line, NS0-derived human PDGF R alpha protein Human PDGF R alpha (Met1 - Glu524) Accession # P16234 IEGRMD Human IgG1 (Pro100 - Lys330) N-terminus C-terminus

2020 USD :

369

2021 USD :

369 USD

alt names :

alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A, CD140a, CD140a antigen, EC 2.7.10, EC 2.7.10.1, MGC74795, PDGFR alpha, PDGFR2, PDGFRA, PDGFRA/BCR fusion, PDGF-R-alpha, platelet-derived growth factor receptor, alpha polypeptide, rearranged-in-hypereosinophilia-platelet derived growth factor receptor alphafusion protein, RHEPDGFRA

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.