product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human PDGF R alpha Fc Chimera Protein, CF
catalog :
6765-PR-050
quantity :
50 ug
price :
428 USD
more info or order :
R&D Systems product webpage
citations: 4
Reference
Braun B, Laib Sampaio K, Kuderna A, Widmann M, Sinzger C. Viral and Cellular Factors Contributing to the Hematogenous Dissemination of Human Cytomegalovirus via Polymorphonuclear Leukocytes. Viruses. 2022;14: pubmed publisher
Park J, Gill K, Aghajani A, Heredia J, Choi H, Oberstein A, et al. Engineered receptors for human cytomegalovirus that are orthogonal to normal human biology. PLoS Pathog. 2020;16:e1008647 pubmed publisher
Stegmann C, Hochdorfer D, Lieber D, Subramanian N, Stöhr D, Laib Sampaio K, et al. A derivative of platelet-derived growth factor receptor alpha binds to the trimer of human cytomegalovirus and inhibits entry into fibroblasts and endothelial cells. PLoS Pathog. 2017;13:e1006273 pubmed publisher
Wu Y, Prager A, Boos S, Resch M, Brizic I, Mach M, et al. Human cytomegalovirus glycoprotein complex gH/gL/gO uses PDGFR-α as a key for entry. PLoS Pathog. 2017;13:e1006281 pubmed publisher
product information
brand :
R&D Systems
master code :
6765-PR
SKU :
6765-PR-050
product name :
Recombinant Human PDGF R alpha Fc Chimera Protein, CF
description :
The Recombinant Human PDGF R alpha Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human PDGF R alpha Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
PDGF R alpha
category :
Proteins and Enzymes
unit sizes :
50 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
observed molecular weight :
110-130 kDa, reducing conditions
theoretical molecular weight :
82.8 kDa (monomer)
gene symbol :
PDGFRA
details of functionality :
Measured by its ability to inhibit the biological activity of PDGF-AB or PDGF-AA using NR6R-3T3 mouse fibroblast cells. Raines, E.W. et al . (1985) Methods Enzymol. 109 :749. The ED50 for this effect is 0.2-1 µg/mL in the presence of 100 ng/mL recombinant human PDGF-AB.
endotoxin note :
<0.01 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P16234
applications :
Bioactivity
source :
NS0-derived Recombinant Human PDGF R alpha Fc Chimera Protein, CF
USD :
428 USD
alt names :
alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A, CD140a, CD140a antigen, EC 2.7.10, EC 2.7.10.1, MGC74795, PDGFR alpha, PDGFR2, PDGFRA, PDGFRA/BCR fusion, PDGF-R-alpha, platelet-derived growth factor receptor, alpha polypeptide, rearranged-in-hypereosinophilia-platelet derived growth factor receptor alphafusion protein, RHEPDGFRA
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.