product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human EphA7 Fc Chimera Protein, CF
catalog :
6756-A7-050
quantity :
50 ug
price :
432 USD
more info or order :
R&D Systems product webpage
citations: 2
Reference
El Fakiri M, Regupathy A, Uhlmann L, Ayada N, Geis N, Domogalla L, et al. Development and preclinical characterization of a novel radiotheranostic EphA2-targeting bicyclic peptide. Theranostics. 2024;14:4701-4712 pubmed publisher
Cha J, Chan L, Wang Y, Chu Y, Wang C, Lee H, et al. Ephrin receptor A10 monoclonal antibodies and the derived chimeric antigen receptor T cells exert an antitumor response in mouse models of triple-negative breast cancer. J Biol Chem. 2022;298:101817 pubmed publisher
product information
master code :
6756-A7
SKU :
6756-A7-050
product name :
Recombinant Human EphA7 Fc Chimera Protein, CF
unit size :
50 ug
description :
The Recombinant Human EphA7 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human EphA7 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
EphA7
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
observed molecular weight :
95-105 kDa, reducing conditions
theoretical molecular weight :
85.7 kDa
gene symbol :
EPHA7
details of functionality :
Measured by its binding ability in a functional ELISA. When Recombinant Human (rh) EphA7 Fc Chimera is coated at 2 ╡g/mL (100 ╡L/well), the concentration of biotinylayed rhEphrin-A4 Fc Chimera that produces 50% of the optimal binding response is found to be approximately 1.5 - 6 ng/mL.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
NP_004431
applications :
Bioactivity
source long :
Mouse myeloma cell line, NS0-derived human EphA7 protein Human EphA7 (Met1 - Val555) Accession # NP_004431 IEGRMD Human IgG1 (Pro100 - Lys330) N-terminus C-terminus
source short :
NS0
USD :
432 USD
alt names :
Cek11, Ebk, EC 2.7.10, EC 2.7.10.1, EHK3, EHK-3, EK11, EPH homology kinase 3, Eph homology kinase-3, EPH receptor A7, EphA7, EPH-like kinase 11, ephrin type-A receptor 7, HEK11, Mdk1, receptor protein-tyrosine kinase HEK11, tyrosine-protein kinase receptor EHK-3
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.