product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human IGFBP-2 Protein, CF
catalog :
674-B2-025
quantity :
25 ug
price :
377 USD
more info or order :
citations: 8
Reference |
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Wirthgen E, Goumon S, Kunze M, Walz C, Spitschak M, Tuchscherer A, et al. Effects of Transport Duration and Environmental Conditions in Winter or Summer on the Concentrations of Insulin-Like Growth Factors and Insulin-Like Growth Factor-Binding Proteins in the Plasma of Market-Weight Pigs. Front Endocrinol (Lausanne). 2018;9:36 pubmed publisher
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Cortesio C, Jiang W. Mannan-binding lectin-associated serine protease 3 cleaves synthetic peptides and insulin-like growth factor-binding protein 5. Arch Biochem Biophys. 2006;449:164-70 pubmed
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Nakamura M, Miyamoto S, Maeda H, Ishii G, Hasebe T, Chiba T, et al. Matrix metalloproteinase-7 degrades all insulin-like growth factor binding proteins and facilitates insulin-like growth factor bioavailability. Biochem Biophys Res Commun. 2005;333:1011-6 pubmed
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product information
brand :
R&D Systems
master code :
674-B2
SKU :
674-B2-025
product name :
Recombinant Human IGFBP-2 Protein, CF
description :
The Recombinant Human IGFBP-2 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human IGFBP-2 Protein, CF has been validated for the following applications: Bioactivity.
target :
IGFBP-2
category :
Proteins and Enzymes
unit sizes :
25 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
observed molecular weight :
36 kDa, reducing conditions
theoretical molecular weight :
31 kDa
gene symbol :
IGFBP2
details of functionality :
Measured by its ability to inhibit the biological activity of IGF-I or IGF-II on MCF-7 human breast cancer cells. Karey, K.P. et al . (1988) Cancer Research 48 :4083. The ED50 for this effect is 0.03-0.09 µg/mL in the presence of 14 ng/mL rhIGF-II.
endotoxin note :
<1.0 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
CAA34373
applications :
Bioactivity
source :
NS0-derived Recombinant Human IGFBP-2 Protein, CF
USD :
377 USD
alt names :
BP2, IBP2, IBP-2, IGF-binding protein 2, IGFBP2, IGFBP-2, IGF-BP53, insulin-like growth factor binding protein 2 (36kD), insulin-like growth factor binding protein 2, 36kDa, insulin-like growth factor-binding protein 2
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information

R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.
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