Recombinant Human IFN-gamma R1 Protein | R&D Systems 673-IR-100 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human IFN-gamma R1 Protein

catalog :

673-IR-100

quantity :

100 ug

price :

456 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Kleemann J, Steinhorst K, K xf6 nig V, Z xf6 ller N, Cinatl J, xd6 zistanbullu D, et al. Functional Downregulation of PD-L1 and PD-L2 by CpG and non-CpG Oligonucleotides in Melanoma Cells. Cancers (Basel). 2022;14: pubmed publisher
Minutti C, Garcia Fojeda B, Saenz A, de Las Casas Engel M, Guillamat Prats R, de Lorenzo A, et al. Surfactant Protein A Prevents IFN-?/IFN-? Receptor Interaction and Attenuates Classical Activation of Human Alveolar Macrophages. J Immunol. 2016;197:590-8 pubmed publisher
Wong J, Muthuswamy R, Bartlett D, Kalinski P. IL-18-based combinatorial adjuvants promote the intranodal production of CCL19 by NK cells and dendritic cells of cancer patients. Oncoimmunology. 2013;2:e26245 pubmed
Sarrazin S, Bonnaffé D, Lubineau A, Lortat Jacob H. Heparan sulfate mimicry: a synthetic glycoconjugate that recognizes the heparin binding domain of interferon-gamma inhibits the cytokine activity. J Biol Chem. 2005;280:37558-64 pubmed

product information

brand :

R&D Systems, a Bio-Techne brand

catalog number base :

673-IR

SKU :

673-IR-100

product name :

Recombinant Human IFN-gamma R1 Protein

description :

The Recombinant Human IFN-gamma R1 Protein from R&D Systems is derived from NS0. The Recombinant Human IFN-gamma R1 Protein has been validated for the following applications: Bioactivity.

target :

IFN-gamma R1/CD119

unit size :

100 ug

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

observed molecular weight :

40 kDa and 50 kDa, reducing conditions

theoretical molecular weight :

25 kDa

gene symbol :

IFNGR1

details of functionality :

Measured by its ability to inhibit rhIFN-gamma mediated protection of HeLa human cervical epithelial carcinoma cells to viral lysis. Meager, A. (1987) in Lymphokines and Interferons, a Practical Approach. Clemens, M.J. et al . (eds): IRL Press. 129. The ED50 for this effect is 1-3 µg/mL in the presence of 2 ng/mL rhIFN-gamma .

endotoxin note :

<1.0 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P15260.1

applications :

Bioactivity

product keywords :

673-IR, rhIFN-g R1, hIFN-g R1,, 673IR, IFN-gR1, IFNgammaR1, INF- R1, IFN- R1, IFN- R1, IFN-g R1, IFN-gR1, IFN gamma R1, Interferon Receptor, IFN-gR1, IFN-gRalpha IFN-g Ralpha, IFN-gamma Receptor 1, Interferon-gamma Receptor 1, INF-g R1, INF-gR1, INF gamma R1, cytokine, zika

source :

NS0-derived Recombinant Human IFN-gamma R1 Protein

USD :

447

USD 2025 :

456 USD

alt names :

AVP, type 2, CD119, CD119 antigen, FLJ45734, IFN-gamma receptor 1, IFNgammaR1, IFN-gamma-R1, IFNGR, IFN-gR1, IFNGR1, immune interferon receptor 1, interferon gamma receptor 1, interferon-gamma receptor alpha chain, type 2

more info or order :

R&D Systems product webpage