product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse Complement Component C2 Protein, CF
catalog :
6725-SE-010
quantity :
10 ug
price :
456 USD
more info or order :
R&D Systems product webpage
citations: 1
Reference
Zhou T, Li Y, Li X, Zeng F, Rao Y, He Y, et al. Microglial debris is cleared by astrocytes via C4b-facilitated phagocytosis and degraded via RUBICON-dependent noncanonical autophagy in mice. Nat Commun. 2022;13:6233 pubmed publisher
product information
master code :
6725-SE
SKU :
6725-SE-010
product name :
Recombinant Mouse Complement Component C2 Protein, CF
unit size :
10 ug
description :
The Recombinant Mouse Complement Component C2 Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse Complement Component C2 Protein, CF has been validated for the following applications: Enzyme Activity.
target :
Complement Component C2
category :
Proteins and Enzymes
buffer :
Supplied as a 0.2 ╡m filtered solution in Sodium Acetate and NaCl.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Mouse
observed molecular weight :
66-75 kDa 90-110 kDa, reducing conditions
theoretical molecular weight :
58 kDa and 84 kDa
gene symbol :
C2
details of functionality :
Measured by its ability to cleave a colorimetric peptide substrate, N-carbobenzyloxy-Gly-Arg-ThioBenzyl ester (Z-GR-SBzl), in the presence of 5,5ÆDithio-bis (2-nitrobenzoic acid) (DTNB). Edwards, K.M. et al . (1999) J. Biol. Chem. 274 :30468. The specific activity is 100 pmol/min/╡g, as measured under the described conditions.
endotoxin note :
<1.0 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
O70350
applications :
Enzyme Activity
source long :
Mouse myeloma cell line, NS0-derived mouse Complement Component C2 protein Met1-Leu760, with a C-terminal 6-His tag.
source short :
NS0
USD :
456 USD
alt names :
C2, C3/C5 convertase, CO2, complement C2, complement component 2, complement component C2, DKFZp779M0311, EC 3.4.21, EC 3.4.21.43
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after opening.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.