This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human gp130 Fc Chimera Protein, CF
catalog :
671-GP
quantity :
100 ug
price :
339 USD
citations: 5
| Reference |
|---|
Chollangi S, Mather T, Rodgers K, Ash J. A unique loop structure in oncostatin M determines binding affinity toward oncostatin M receptor and leukemia inhibitory factor receptor. J Biol Chem. 2012;287:32848-59 pubmed
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Abir R, Fisch B, Jin S, Barnnet M, Freimann S, van den Hurk R, et al. Immunocytochemical detection and RT-PCR expression of leukaemia inhibitory factor and its receptor in human fetal and adult ovaries. Mol Hum Reprod. 2004;10:313-9 pubmed
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McLoughlin R, Witowski J, Robson R, Wilkinson T, Hurst S, Williams A, et al. Interplay between IFN-gamma and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation. J Clin Invest. 2003;112:598-607 pubmed
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product information
brand :
R&D Systems
master code :
671-GP
SKU :
671-GP-100
product name :
Recombinant Human gp130 Fc Chimera Protein, CF
description :
The Recombinant Human gp130 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human gp130 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
gp130/CD130
category :
Proteins and Enzymes
unit size :
100 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Human
observed molecular weight :
115-130 kDa, reducing conditions
theoretical molecular weight :
95 kDa (monomer)
gene symbol :
IL6ST
details of functionality :
Measured by its ability to inhibit IL-6-dependent proliferation of the 7TD1 mouse hybridoma cells in the presence of Recombinant Human IL-6 R alpha (Catalog # 227-SR ). The ED50 for this effect is 0.65-6.5 ng/mL.
endotoxin note :
<0.01 EU per 1 µg of the protein by the LAL method.
catalog number base :
671-GP
accessionNumbers :
P40189
applications :
Bioactivity
source :
Mouse myeloma cell line, NS0-derived human gp130 protein Human gp130 (Glu23-Ile618) Accession # P40189 DIEGRMD Human IgG1 (Pro100-Lys330) 6-His tag N-terminus C-terminus
2020 USD :
339
2021 USD :
339 USD
alt names :
CD130, CD130 antigen, CDw130, DKFZp564F053, gp130, gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form, IL-6 receptor subunit beta, IL-6R subunit beta, IL-6RB, IL-6R-beta, IL6ST, interleukin 6 signal transducer (gp130, oncostatin M receptor), interleukin receptor beta chain, interleukin-6 receptor subunit beta, Interleukin-6 signal transducer, Membrane glycoprotein 130, membrane glycoprotein gp130, Oncostatin-M receptor subunit alpha
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.
questions and comments