This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human GFR alpha-3 Fc Chimera Protein, CF
catalog :
670-FR
quantity :
100 ug
price :
359 USD
citations: 2
Reference
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher
Lu B, PereiraPerrin M. A novel immunoprecipitation strategy identifies a unique functional mimic of the glial cell line-derived neurotrophic factor family ligands in the pathogen Trypanosoma cruzi. Infect Immun. 2008;76:3530-8 pubmed publisher
product information
brand :
R&D Systems
master code :
670-FR
SKU :
670-FR-100
product name :
Recombinant Human GFR alpha-3 Fc Chimera Protein, CF
description :
The Recombinant Human GFR alpha-3 Fc Chimera Protein, CF from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Human GFR alpha-3 Fc Chimera Protein, CF has been validated for the following applications: Binding Activity.
target :
GFR alpha-3/GDNF R alpha-3
category :
Proteins and Enzymes
unit size :
100 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Human
observed molecular weight :
67 kDa, reducing conditions
theoretical molecular weight :
67 kDa (monomer)
gene symbol :
GFRA3
details of functionality :
Binding of R D Systems’ human GFR alpha-3/Fc Chimera to immobilized Artemin has been reported. Baloh, R. et al . (1998) Neuron 21 :1291. Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human Artemin (Catalog # 2589-AR ) at 1 µg/mL can bind Recombinant Human GFR alpha-3/GDNF R alpha-3 Fc Chimera with an apparent Kd 1 nM.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
catalog number base :
670-FR
accessionNumbers :
AAC24355
applications :
Binding Activity
source :
Spodoptera frugiperda , Sf 21 (baculovirus)-derived human GFR alpha-3/GDNF R alpha-3 protein Human GFR alpha-3 (Gly31-Trp382) Accession # AAC24355 IEGRMD Human IgG1 (Pro100-Lys330) 6 His tag Human GFR alpha-3 (Asp32-Trp382) Accession # AAC24355 IEGRMD Human IgG1 (Pro100-Lys330) 6 His tag N-terminus C-terminus
extended description :
A New rh GFRa-3 is Now Available! Enhanced purity; Mammalian cell expressed; No His-tag!
2020 USD :
359
2021 USD :
359 USD
product details :
A New rh GFRa-3 is Now Available! Enhanced purity; Mammalian cell expressed; No His-tag!
alt names :
GDNF family receptor alpha 3, GDNF family receptor alpha-3, GDNF R alpha-3, GDNF receptor alpha-3, GDNFR-alpha-3, GFR alpha3, GFRa-3, GFRA3, GFR-alpha-3, glial cell line-derived neurotrophic factor receptor alpha-3, GPI-linked receptor
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.