This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Twisted Gastrulation (TSG) Protein, CF
catalog :
6684-TG-050
quantity :
50 ug
price :
300 USD
citations: 3
Reference
Esser J, Steiner R, Deckler M, Schmitt H, Engert B, Link S, et al. Extracellular bone morphogenetic protein modulator BMPER and twisted gastrulation homolog 1 preserve arterial-venous specification in zebrafish blood vessel development and regulate Notch signaling in endothelial cells. FEBS J. 2018;285:1419-1436 pubmed publisher
Olsen O, Wader K, Misund K, Våtsveen T, Rø T, Mylin A, et al. Bone morphogenetic protein-9 suppresses growth of myeloma cells by signaling through ALK2 but is inhibited by endoglin. Blood Cancer J. 2014;4:e196 pubmed publisher
Yamada S, Nakamura J, Asada M, Takase M, Matsusaka T, Iguchi T, et al. Twisted gastrulation, a BMP antagonist, exacerbates podocyte injury. PLoS ONE. 2014;9:e89135 pubmed publisher
product information
master code :
6684-TG
SKU :
6684-TG-050
product name :
Recombinant Human Twisted Gastrulation (TSG) Protein, CF
unit size :
50 ug
description :
The Recombinant Human Twisted Gastrulation (TSG) Protein, CF from R&D Systems is derived from CHO. The Recombinant Human Twisted Gastrulation (TSG) Protein, CF has been validated for the following applications: Bioactivity.
target :
TSG
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
observed molecular weight :
35-43 kDa, reducing conditions
theoretical molecular weight :
22.1 kDa
gene symbol :
TWSG1
details of functionality :
Measured by its ability to inhibit BMP-6-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 for this effect is 4-16 ╡g/mL in the presence of 100 ng/mL of Recombinant Human BMP-6 (Catalog # 507-BP).
endotoxin note :
<0.01 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
NP_065699
applications :
Bioactivity
source long :
Chinese Hamster Ovary cell line, CHO-derived human TSG protein Met1-Phe223
source short :
CHO
USD :
300 USD
alt names :
TSGtwisted gastrulation protein homolog 1, twisted gastrulation homolog 1 (Drosophila), TWSG1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.