Recombinant Human Fc epsilon RI alpha Protein, CF | R&D Systems 6678-FC-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Fc epsilon RI alpha Protein, CF

catalog :

6678-FC-050

quantity :

50 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 1

Reference
Metz M, Sussman G, Gagnon R, Staubach P, Tanus T, Yang W, et al. Fenebrutinib in H1 antihistamine-refractory chronic spontaneous urticaria: a randomized phase 2 trial. Nat Med. 2021;27:1961-1969 pubmed publisher

product information

master code :

6678-FC

SKU :

6678-FC-050

product name :

Recombinant Human Fc epsilon RI alpha Protein, CF

unit size :

50 ug

description :

The Recombinant Human Fc epsilon RI alpha Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Fc epsilon RI alpha Protein, CF has been validated for the following applications: Bioactivity.

target :

Fc epsilon RI alpha

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

45-58 kDa, reducing conditions

theoretical molecular weight :

21.9 kDa

gene symbol :

FCER1A

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Human Fc epsilon RI alpha is immobilized at 0.1 ╡g/mL (100 ╡L/well), the concentration of human IgE that produces 50% of the optimal binding response is found to be approximately 0.0200-0.200 ╡g/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

top caption :

Graph showing bioactivity of Human Fc epsilon RI alpha protein

accessionNumbers :

NP_001992

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived human Fc epsilon RI alpha protein Val26-Gln205, with a C-terminal 6-His tag

source short :

NS0

USD :

432 USD

alt names :

Fc epsilon RI alpha-chain, Fc fragment of IgE receptor Ia, Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide, Fc IgE receptor, alpha polypeptide, FCE1A, Fc-epsilon RI-alpha, FcepsilonRI alpha chain, FcepsilonRIalpha, FCER1A, FcERI, FceRIa, high affinity immunoglobulin epsilon receptor alpha-subunit, high affinity immunoglobulin epsilon receptor subunit alpha, igE Fc receptor subunit alpha, immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage