product summary
Loading...
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Neurexin 2 alpha Isoform 2 Fc Chimera, CF
catalog :
6636-NX-025
quantity :
25 ug
price :
456 USD
more info or order :
R&D Systems product webpage
citations: 1
Reference
Brito Moreira J, Lourenco M, Oliveira M, Ribeiro F, Ledo J, Diniz L, et al. Interaction of amyloid-β (Aβ) oligomers with neurexin 2α and neuroligin 1 mediates synapse damage and memory loss in mice. J Biol Chem. 2017;292:7327-7337 pubmed publisher
product information
master code :
6636-NX
SKU :
6636-NX-025
product name :
Recombinant Human Neurexin 2 alpha Isoform 2 Fc Chimera, CF
unit size :
25 ug
description :
The Recombinant Human Neurexin 2 alpha Isoform 2 Fc Chimera, CF from R&D Systems is derived from CHO. The Recombinant Human Neurexin 2 alpha Isoform 2 Fc Chimera, CF has been validated for the following applications: Bioactivity.
target :
Neurexin 2 alpha/NRXN2a
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
observed molecular weight :
200-250 kda, reducing conditions
theoretical molecular weight :
193 kDa (monomer)
gene symbol :
NRXN2
details of functionality :
Measured by its binding ability in a functional ELISA. When Recombinant Human Neurexin 2 alpha /NRXN2a Fc Chimera is coated at 2 ╡g/mL, biotinylated recombinant rat NXPH-1 binds with an apparent KD 10 nM.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
NP_620060
applications :
Bioactivity
source long :
Chinese Hamster Ovary cell line, CHO-derived human Neurexin 2 alpha/NRXN2a protein Human Neurexin 2 alpha (Met1 - Thr1566) Accession # NP_620060 IEGRMD Human IgG1 (Pro100 - Lys330) N-terminus C-terminus
source short :
CHO
USD :
456 USD
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.