Recombinant Mouse LBP Protein, CF | R&D Systems 6635-LP-025/CF product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse LBP Protein, CF

catalog :

6635-LP-025/CF

quantity :

25 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 5

Reference
Devant P, Bor x161 i x107 E, Ngwa E, Xiao H, Chouchani E, Thiagarajah J, et al. Gasdermin D pore-forming activity is redox-sensitive. Cell Rep. 2023;42:112008 pubmed publisher
Wang X, Li Z, Bai Y, Zhang R, Meng R, Chen F, et al. A small molecule binding HMGB1 inhibits caspase-11-mediated lethality in sepsis. Cell Death Dis. 2021;12:402 pubmed publisher
Cornelius D, Travis O, Tramel R, Borges Rodriguez M, Baik C, Greer M, et al. NLRP3 inflammasome inhibition attenuates sepsis-induced platelet activation and prevents multi-organ injury in cecal-ligation puncture. PLoS ONE. 2020;15:e0234039 pubmed publisher
Cornelius D, Baik C, Travis O, White D, Young C, Austin Pierce W, et al. NLRP3 inflammasome activation in platelets in response to sepsis. Physiol Rep. 2019;7:e14073 pubmed publisher
Okamoto N, Mizote K, Honda H, Saeki A, Watanabe Y, Yamaguchi Miyamoto T, et al. Funiculosin variants and phosphorylated derivatives promote innate immune responses via the Toll-like receptor 4/myeloid differentiation factor-2 complex. J Biol Chem. 2017;292:15378-15394 pubmed publisher

product information

master code :

6635-LP/CF

SKU :

6635-LP-025/CF

product name :

Recombinant Mouse LBP Protein, CF

unit size :

25 ug

description :

The Recombinant Mouse LBP Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse LBP Protein, CF has been validated for the following applications: Bioactivity.

target :

LBP

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in MES, NaCl, PEG and CHAPS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

observed molecular weight :

60-65 kDa, reducing conditions

theoretical molecular weight :

51.5 kDa

gene symbol :

Lbp

details of functionality :

Measured by its ability to enhance LPS-stimulated IL-8 secretion by THP-1 human acute monocytic leukemia cells. The ED50 for this effect is 0.5-3 ng/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_032515

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived mouse LBP protein Gly25-Val481 (Ser102Arg, Tyr284His), with a C-terminal 6-His tag

source short :

NS0

USD :

432 USD

alt names :

lipopolysaccharide binding protein, lipopolysaccharide-binding protein, LPS-binding protein, MGC22233

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage